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Compound Chinese medicinal formulation for treating chronic atrophic gastritis and its preparing method

A technology for compound preparations and traditional Chinese medicines, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, drug combinations, etc.

Active Publication Date: 2007-07-25
SHANGHAI LEIYUNSHANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, there have been many Chinese patent medicines mainly for the treatment of chronic superficial gastritis, but there are few Chinese patent medicines for the treatment of atrophic gastritis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0161] Recipe: Pseudostellaria ginseng 1500g, red peony root 1500g, Guangxi blood dried powder 333g, Atractylodes macrocephala 1500g, salvia miltiorrhiza 1500g, bupleurum 1000g, scutellaria baicalensis 1500g, white peony root 1500g, licorice 1000g, water thread grass 5000g, Shuyangquan 3000g, sarsaparilla 5000g, Xu Changqing 2500g, Zijinniu 2500g, Wood Butterfly 1500g.

[0162] The above fifteen flavors were steam distilled from Xu Changqing and Bupleurum, collected 17.5L of distillate, and stored in another container, added other medicinal materials except Guangxi dried blood, added 320L of water, extracted twice, combined the extracts, filtered, and concentrated in vacuum to relative Density of 1.14 (60 ~ 65 ℃) extract, add Xu Changqing, Bupleurum and other distillates and dextrin 3.2kg spray-dried, dry powder mixed with Guangxi dried blood powder, made into granules, paeoniflorin content 0.41%.

Embodiment 2

[0164] According to the prescription of Example 1, the above fifteen flavors, Xu Changqing and Bupleurum chinensis are steam distilled, 16L of the distillate is collected, and stored in a separate container, and other medicinal materials are added except Guangxi dried blood, and 300L of water is added, and the extraction is performed twice, and the extracts are combined and filtered. , concentrated in vacuum to the extract with a relative density of 1.14 (60-65°C), adding distillates such as Xu Changqing and Bupleuri and 3.2kg of dextrin to spray-dry, and mixing the dry powder with Guangxi dried blood powder, and making it into pills. . Paeoniflorin content 0.41%.

Embodiment 3

[0166] According to the prescription of Example 1, the above fifteen flavors, Xu Changqing and Bupleurum chinensis are steam distilled, 18L of the distillate is collected, stored in a separate container, and other medicinal materials are added except Guangxi dried blood, 350L of water is added, the extraction is performed twice, the extracts are combined, and filtered , vacuum concentrated to the extract with a relative density of 1.25 (60-65°C), add 35L of ethanol, stir, filter, recover the ethanol, add distillates such as Xu Changqing, Bupleurum radix and 1kg of dextrin to spray dry, dry powder and Guangxi dried blood The powder is mixed evenly, granulated, compressed into tablets, coated, and obtained. Paeoniflorin content 0.67%.

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Abstract

The invention involves a kind of Chinese native medicine compound prescription preparation which is able to treat the chronic withering stomach medicine and the preparing method. The Chinese native medicine compound prescription preparation is composed by Radix Paeudostellariae, Radix Paeoniae Rubra, Resina Draconis, Rhizoma Aruactylodis Macrocephalae, Radix Salviae Miltinrrhizae, Radix Bupleuri, Radix Scutellariae, Radix Paeoniae Alba, Radix Glycyrrhizae, Herba Hedyotidis Corymosae, Radix Cynanchi Paniculati, Rhizoma Smilacis Chinensis, Radix Cynanchi Paniculati, Hriba Ardisiae Japonicae, Seen Oroxyli.The invention compound prescription Chinese native medicine preparation which can treat the chronic withering gastritis can adjust the organism function, improves the environment in the stomach, enhances the power, protects the barrier of gastric mucosa, the improvement mucous membrane blood stream, Thus provides the good environment for repairing, regeneration the gastric mucosa arteries veins body withers.Also the dosage-form is simple, is convenient to take.

Description

Technical field: [0001] The invention relates to a Chinese medicine compound preparation and a preparation method, in particular to a Chinese medicine compound preparation and a preparation method for treating chronic atrophic gastritis. Background technique: [0002] Chronic gastritis is a common and frequently-occurring disease, especially chronic atrophic gastritis or those with intestinal gland metaplasia and atypical hyperplasia is a stubborn and intractable digestive tract disease, which has a certain relationship with the incidence of gastric cancer . In 1983, WHO called atrophic gastritis a precancerous state of the stomach, but the accompanying intestinal glandular metaplasia or atypical hyperplasia were precancerous lesions of the stomach. At present, there is still a lack of more effective drugs for the treatment of this disease at home and abroad, and Western medicine only stays in the stage of regular review and close observation. [0003] Although there is no...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K36/889A61K36/71A61K36/53A61K36/481A61K36/36A61K36/284A61K36/27A61P1/04
Inventor 陈忠梁胡春湘乐国祥康爱仙张正光傅子华张镜人张存钧
Owner SHANGHAI LEIYUNSHANG PHARMA
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