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Dentifrice compositions comprising a stable low water, phase comprising polyphosphate and ionic active ingredients

A technology of active ingredients and compositions, applied in the field of dentifrice compositions, which can solve the problems of limited thixotropic properties, high-cost toothpaste, etc.

Inactive Publication Date: 2006-11-29
THE PROCTER & GAMBLE COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the relatively high cost of carrageenan and the thixotropic properties of carrageenan-containing toothpastes are believed to limit the widespread use of carrageenan in dentifrices

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 19

[0095] Example 19 can also be prepared as follows. Glycerin, PEG, dye, active were mixed and stirred for 10 minutes. Vacuum, then add sweetener and binder. The mixture was homogenized twice and vacuumed. Then NaOH solution was added and stirred for at least 3 minutes. Vacuum was applied, then the silica abrasive was added and mixed for at least 8 minutes. Vacuum was applied and stirred for 10 minutes. Add SLS powder and flavor and mix for at least 2 minutes. Then vacuum and homogenize twice. Add polyphosphate and mix for at least 5 minutes until uniform.

Embodiment 20

[0096] Example 20 can also be prepared as follows. The glycerol, PEG and dye were mixed and the mixture was stirred for 5 minutes. Add binder. Homogenize the batch once and apply vacuum. Mix for 5 minutes. NaOH solution was added. Vacuum and stir for 10 minutes. Add active substance. Homogenize once and evacuate. Add the silica abrasive and mix for at least 8 minutes. Add SLS powder and flavor and mix for at least 2 minutes. Then vacuum and homogenize twice. Add polyphosphate and stir for at least 5 minutes until homogeneous.

[0097] The compositions of the present invention exhibit good viscosity and stability. After the matrix has reached equilibrium, the compositions of the present invention have a Brookfield viscosity of from about 30 to about 90 BKU. Table 1 shows the viscosity characteristics of the present composition of Example 12 as a function of time.

[0098] aging days

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PUM

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Abstract

Disclosed are dentifrice compositions comprising in a single phase: (a) from about 0.1 % to about 30 % of one or more linear polyphosphates having an average chain length of about 4 or more; (b) an ionic active ingredient selected from the group consisting of a fluoride ion source, a stannous ion source, a zinc ion source, a copper ion source and mixtures thereof, wherein the ionic active ingredient is present as a solid dispersion in the composition and delivers an effective amount of ionic active when solubilized; (c) a binder system comprised of (i) from about 0.05 % to about 3 % of a thickening agent selected from the group consisting of polysaccharides, carbomers, poloxamers, modified celluloses, and mixtures thereof; and (ii) from about 0.1 % to about 70 % of at least one humectant; wherein the dentifrice composition has a total water content of less than about 10 %. Further disclosed are methods for stabilizing dentifrice compositions by providing such a binder system.

Description

field of invention [0001] The present invention relates to dentifrice compositions comprising a low water content phase comprising polyphosphate and ionically active comprising fluoride and / or metal ions such as stannous, zinc and copper ions Element. Background of the invention [0002] The compositions of the present invention are dentifrices comprising a phase providing an effective amount of polyphosphate and an ionic active such as fluoride ions and / or metal ions such as stannous, zinc and copper ions, such phases having Low levels of water in which the components are stable also include binder systems that provide adequate gelation in low water, non-polar humectant systems. [0003] Although such actives have previously been used in dentifrices to promote oral health, providing these actives simultaneously in a stable single phase has proven challenging for a number of reasons. Certain polyphosphates, which are effective anti-tartar agents, are known to be unstable i...

Claims

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Application Information

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IPC IPC(8): A61K8/19A61K8/72A61Q11/00A61K8/21A61K8/24A61K8/27A61K8/29A61K8/34A61K8/73A61K8/81A61K8/86A61K8/90
CPCA61Q11/00A61K8/19A61K8/21A61K8/24A61K8/27A61K8/73A61K8/731A61K8/8147A61K8/90
Inventor J·岳L·朱L·陈Y·程T·徐A·D·维勒Y·王
Owner THE PROCTER & GAMBLE COMPANY
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