Artificial tear
A technology of artificial tears and water-soluble chitin is applied in sensory diseases, drug combination and other directions, and achieves the effects of simple preparation method, good protection effect and good moisturizing property.
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0008] Take 3.0g of hydroxyethyl chitin, 0.2g of quaternized chitosan, 5g of sodium chloride, 0.4g of calcium chloride, 3.4g of potassium dihydrogen phosphate, and 3.7g of disodium hydrogen phosphate, and dissolve them in 400ml of water for injection. Then filter, dilute the filtrate to 1000ml with water for injection, sterilize with flowing steam at 100°C, and pack it separately to obtain a colorless, clear and slightly viscous artificial tear preparation. When it is dropped into the eyes, it can replenish water, moisten the surface of the eyes, and produce a mucus and water-absorbing solution to cover the surface of the eyes, which can eliminate eye discomfort, protect the eyes, and effectively relieve and treat dry eye syndrome.
[0009] The quaternized chitosan in the present embodiment is to use hydroxypropyl chitosan or chitosan oligosaccharide (ChitosanOLigosaccharide, molecular weight≤5000) in alkaline isopropanol medium, molar ratio 1: 0.8-1.2 under stirring Proportio...
Embodiment 2
[0011] Take 4g of hydroxypropyl chitosan, 0.1g of quaternized chitosan, 8g of sodium chloride, 0.2g of calcium chloride, 1.2g of potassium dihydrogen phosphate, 4.3g of disodium hydrogen phosphate, and dissolve it with 400ml of water for injection , filtered to remove insoluble matter, and the filtrate was diluted to 1000ml with water for injection, sterilized by circulating steam at 100°C and sub-packaged to form an artificial tear preparation, which also has the effect of the product in Example 1.
Embodiment 3
[0013] Take chitosan oligosaccharide, also known as chitosan oligosaccharide (molecular weight ≤ 5000) 5.0g, quaternized chitosan 0.3g, sodium chloride 6.0g, calcium chloride 0.6g, potassium dihydrogen phosphate 2.0g, disodium hydrogen phosphate 3.8g, first dissolved with 400-500ml of water for injection, filtered, the filtrate was diluted to 1000ml with water for injection, sterilized by circulating steam at 100°C, and subpackaged to form an artificial tear preparation, which also has the effect of the product in Example 1.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com