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Magnetorheological elastic composite film surface stress biosensor

A magnetorheological elasticity and biosensor technology, applied in the field of biosensors, can solve the problems of poor anti-interference ability and low sensitivity of biological detection, and achieve the effect of strong response speed, high sensitivity at low concentration, and improved sensitivity

Pending Publication Date: 2022-07-22
TAIYUAN UNIV OF TECH
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Problems solved by technology

Overcome the problems of low biological detection sensitivity and poor anti-interference ability at low concentrations

Method used

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  • Magnetorheological elastic composite film surface stress biosensor
  • Magnetorheological elastic composite film surface stress biosensor
  • Magnetorheological elastic composite film surface stress biosensor

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Embodiment Construction

[0026] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention clearer, the present invention will be further described in detail with reference to the embodiments and the accompanying drawings. It should be understood that the specific embodiments described herein are only used to explain the present invention, but not to limit the present invention. The technical solutions of the present invention will be described in detail below with reference to the embodiments and the accompanying drawings, but the protection scope is not limited by this.

[0027] like Figure 1-3 As shown in the figure, the present embodiment discloses a magnetorheological elastic composite film surface stress biosensor. The biosensor consists of a substrate 1, a micromagnetic field layer 14, a magnetorheological elastic composite film layer 13, and a microfluidic tunnel from bottom to top. 7. The detection area 8 and the two ends of the...

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Abstract

The invention belongs to the technical field of biosensors, and relates to a magneto-rheological elastic composite film surface stress biosensor. The problems of low biological detection sensitivity and poorer anti-interference capability under low concentration are solved; comprising a magnetorheological elastic composite film layer, the periphery of the magneto-rheological elastic composite film layer is provided with a deformation space; the magneto-rheological elastic composite film layer comprises a biological recognition layer, a piezoelectric / piezoresistive layer and a magneto-rheological elastic layer which are sequentially arranged in an overlapped mode. The surface of the biological recognition layer is modified with a probe; the magneto-rheological elastic layer and the biological recognition layer are respectively connected with an electrode; the electrode is in contact with the piezoelectric / piezoresistive layer; the magneto-rheological elastic layer deforms under the action of a magnetic field so as to amplify the surface stress of the biological recognition layer; the device has the characteristics of miniaturization, interference resistance, high precision and capability of simultaneously acquiring a plurality of sensing information amounts.

Description

technical field [0001] The invention belongs to the technical field of biosensors, and relates to a magnetorheological elastic composite film surface stress biosensor. Background technique [0002] With the development of bio-MEMS technology, microstructure has been widely concerned and applied in the field of biochemical sensing. Surface stress biosensor is a kind of biosensor, which can be used in clinical medical diagnosis, biochemical detection, new drug discovery and other fields. The detection principle of surface stress biosensors is to modify the sensor with specific probes to realize the qualitative analysis of the biomolecules to be tested; after the molecules to be tested are combined with their corresponding probes, the sensitive parts of the sensor will undergo slight deformation, and different concentrations of the molecules to be tested will produce small deformations. The magnitude of the stress generated by the combination with the probe is different, and t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01L1/12G01L9/16G01N27/72G01N27/74
CPCG01L1/125G01L9/16G01N27/72G01N27/74
Inventor 葛阳桑胜波谭秋芸赵冬姜交林吴凯乐肖鹏利
Owner TAIYUAN UNIV OF TECH
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