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New application of ginseng root strengthening oral liquid in preventing or treating sicca syndrome

A technology of Sjogren's syndrome and oral liquid, which is applied in the field of ginseng Guben oral liquid to prevent or treat Sjögren's syndrome. It can solve the problems of delayed treatment timing, easy to cover up the disease, and large side effects, so as to increase saliva secretion and regulate immunity. The effect of balancing and suppressing hyperactivity of humoral immunity

Inactive Publication Date: 2022-06-24
SHANDONG NEWTIME PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine has no effective method for Sjogren's syndrome, and can only relieve symptoms through hormones and immunosuppressants. These drugs temporarily relieve the condition, and have large side effects. After stopping the drug, it is easy to relapse, easily cover up the condition, and delay the best time for treatment
At present, there is no relevant report that Ginseng Guben Oral Liquid can be used to prevent or treat Sjögren's syndrome

Method used

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Examples

Experimental program
Comparison scheme
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Embodiment Construction

[0028] The present invention is further illustrated by the following examples. It should be correctly understood that the embodiments of the present invention are only used to illustrate the present invention, rather than to limit the present invention. Therefore, simple improvements to the present invention under the premise of the method of the present invention all belong to the scope of protection of the present invention.

[0029] Animal experiment

[0030] The SD rat model of Sjögren's syndrome was established, and the effect of Ginseng Guben Oral Liquid on the saliva volume, peripheral blood T lymphocyte subsets and serum IgG, TNF-α of SD rats with Sjögren's syndrome was observed. T lymphocytes are an important immunocompetent cell, CD4 + cells and CD8 + Cells are two functionally distinct subsets of T lymphocytes that play positive and negative regulatory roles in immune responses, forming T cell networks, CD4 + / CD8 + The ratio represents the overall immune balanc...

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PUM

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a novel application of ginseng root-strengthening oral liquid for preventing or treating sicca syndrome. The ginseng root-strengthening oral liquid is an exclusive variety of the South Thick Pharmacy Co., Ltd., and has the effects of nourishing yin and tonifying qi, strengthening root and strengthening primordial qi, clearing heat and cooling blood, promoting blood circulation to remove blood stasis, nourishing yin and generating body fluid, nourishing yin and moistening dryness, tonifying liver and kidney and the like. Tests prove that the traditional Chinese medicine composition can remarkably improve salivary secretion of model rats, improve T lymphocyte subgroups in peripheral blood of mice and reduce the level of immune globulin in serum, and can be used for preparing the medicine for treating or preventing sicca syndrome.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a new use of ginseng Guben oral liquid for preventing or treating Sjogren's syndrome. Background technique [0002] Sjögren's syndrome is a chronic autoimmune disease that mainly invades the lacrimal glands, salivary glands and other exocrine glands, also known as autoimmune exocrine gland disease. Its pathological mechanism is mainly due to the excessive response of autoimmunity, resulting in the infiltration of a large number of lymphocytes and plasma cells in the exocrine glands, causing the destruction of gland cells and loss of function, resulting in a series of clinical symptoms and manifestations, including keratitis sicca and conjunctivitis. , Xerostomia, decreased saliva secretion, parotid gland soreness, chest tightness and abdominal distension, backache and soft feet, insomnia and night sweats. [0003] Sjögren's syndrome is an autoimmu...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61K9/08A61P1/02A61P27/02A61P37/02
CPCA61K36/258A61K36/804A61K36/40A61K36/8945A61K36/71A61K36/65A61K36/884A61K36/076A61K36/8965A61K36/8968A61K9/0095A61P37/02A61P27/02A61P1/02A61K2300/00
Inventor 孙成磊程国良
Owner SHANDONG NEWTIME PHARMA
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