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Nanometer substance for promoting calcium absorption

A kind of substance and nanotechnology, applied in the field of medicine and health, can solve the problems of long half-life, difficult to achieve the purpose of calcium supplementation, low absorption rate, etc.

Pending Publication Date: 2022-04-15
BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Taking calcium alone, its absorption rate is very low, it is difficult to achieve the purpose of calcium supplementation, and vitamin D can promote the absorption of calcium, so the calcium supplement preparations on the market are almost without exception the compound preparations of calcium and vitamin D
[0003] However, vitamin D is an active substance with hormonal effects. Because it has a long half-life of metabolism in the body and can accumulate in body fat, if you do not pay attention to controlling the dose, no matter children or adults, long-term use or short-term large amounts Taking it will cause a large amount of vitamin D to accumulate in the human body, which will easily cause vitamin D poisoning

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0007] Scutellaria baicalensis charcoal is decocted and extracted, and then dialyzed with a dialysis bag with a molecular weight of 1KDa. The intercepted part in the dialysis bag can be ultrafiltered with a 10KD ultrafiltration tube, and the filtrate part contains Scutellaria baicalensis carbon dots. The carbon dots are mainly composed of C, H and O elements, the pH value is less than 7, and it is acidic. When calcium carbonate fine powder is added, tiny bubbles are generated, which is caused by the carbon dioxide gas produced by the reaction with calcium carbonate. After drying, Scutellaria baicalensis is obtained. The mixture of carbon dots and calcium carbonate is further prepared into granules or tablets by adding conventional auxiliary materials.

Embodiment 2

[0009] After the hawthorn charcoal is decocted and extracted, it is then dialyzed with a dialysis bag with a molecular weight of 1KDa. The intercepted part in the dialysis bag can be ultrafiltered with a 10KD ultrafiltration tube, and the filtrate contains the carbon dots of hawthorn charcoal. The carbon dots are mainly composed of C, H and O elements, the pH value is less than 7, and it is acidic. When calcium carbonate fine powder is added, fine air bubbles are generated, which is caused by the carbon dioxide gas produced by the reaction with calcium carbonate. After drying, the hawthorn is obtained. The mixture of carbon dots and calcium carbonate is further prepared into granules or tablets by adding conventional auxiliary materials.

Embodiment 3

[0011] Jiaosanxian is decocted and extracted, and then dialyzed with a dialysis bag with a molecular weight of 1KDa. The intercepted part in the dialysis bag can be ultrafiltered with a 10KD ultrafiltration tube, and the filtrate contains Jiaosanxian carbon dots. The carbon dots are mainly composed of C, H and O elements, the pH value is less than 7, and it is acidic. When calcium carbonate fine powder is added, tiny bubbles are generated, which is caused by the carbon dioxide gas produced by the reaction with calcium carbonate. After drying, Jiaosanxian is obtained. The mixture of carbon dots and calcium carbonate is further prepared into granules or tablets by adding conventional auxiliary materials.

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Abstract

The invention relates to an application of carbon dots (nano substances / nano particles / particles). The carbon dots are characterized in that raw materials for preparing the carbon dots come from edible plants or traditional Chinese medicines in nature, the carbon dots are soluble in water, the pH value of an aqueous solution is smaller than 7, the solubility of calcium carbonate in water can be remarkably increased, and the bioavailability of the calcium carbonate is improved.

Description

technical field [0001] The invention belongs to the field of medicine and health. Background technique [0002] Calcium is an indispensable life element for the human body. In daily diet, such as milk, fish, seaweed, spinach, etc., the calcium content is relatively high, and calcium is in an ionic state, which is good for absorption. However, relevant research results show that the daily calcium intake cannot meet the health requirements of most people. The results of the third national nutritional survey show that the average daily calcium intake in my country is only 405 mg, which is only about 50% of the recommended supply. Therefore, there is a great demand for calcium supplementation in the market. At present, there are many kinds of calcium supplement preparations on the market. There are more than 1800 kinds of calcium preparation foods and more than 200 kinds of medicines. Taking calcium alone has a very low absorption rate, making it difficult to achieve the purp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/10A61K47/04A61P3/02
Inventor 孔慧王庆国屈会化赵琰张越成金俊鲁放孙紫薇张美龄罗娟
Owner BEIJING UNIV OF CHINESE MEDICINE
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