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Application of theaflavin in preparation of poultry pathogenic bacterium resisting medicine

A technology of avian pathogenic bacteria and theaflavins, applied in the preparation of drugs against avian pathogenic bacteria, in the field of theaflavins, achieving good application prospects and good antibacterial effects

Pending Publication Date: 2022-04-08
INST OF ANIMAL SCI & VETERINARY HUBEI ACADEMY OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are few reports on the antibacterial effects of theaflavins

Method used

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  • Application of theaflavin in preparation of poultry pathogenic bacterium resisting medicine
  • Application of theaflavin in preparation of poultry pathogenic bacterium resisting medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Antibacterial spectrum determination of theaflavins on bacteria:

[0018] 1. Materials

[0019] Mueller-Hinton (MH) broth (purchased from BD Company) was used in drug susceptibility experiments to detect the antibacterial efficacy of drugs.

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Abstract

The invention belongs to the technical field of veterinary drugs, and discloses an application of theaflavin in preparation of a drug for resisting avian pathogenic bacteria. The applicant discovers that theaflavin has the effects of inhibiting the growth of duck-origin chicken bacilli and avian pasteurella and killing the duck-origin chicken bacilli and avian pasteurella, the minimum inhibitory concentration of theaflavin to the duck-origin chicken bacilli is 128 mu g / ml, the minimum bactericidal concentration of theaflavin to the duck-origin chicken bacilli is 512 mu g / ml, the minimum inhibitory concentration of theaflavin to the avian pasteurella is 512 mu g / ml, and the minimum bactericidal concentration of theaflavin to the avian pasteurella is 512 mu g / ml. The toxic and side effects of vaccines, chemical drugs and antibiotics and potential food safety hazards are overcome, and wide application prospects and development values are achieved in the fields of food processing, medicine and breeding industry.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicines, and in particular relates to the application of theaflavins in the preparation of medicines against avian pathogenic bacteria. Background technique [0002] Pasteurella avian is an opportunistic pathogenic bacterium belonging to the genus Pasteurella of the Pasteurella family, which causes the infection of 3-4 month-old rearing poultry and laying poultry, with a mortality rate of 20%-30%. The serotypes of Pasteurella can be divided into five types: A, B, D, E, and F according to the capsular antigen, among which A and F are often the dominant serotypes isolated from sick and dead birds. In addition, the duck-derived Gallibacterium gallis is an opportunistic pathogenic bacterium of the Pasteurellaceae family Gallisbacterium genus. threaten. [0003] The focus of control of poultry Pasteurellaceae diseases is mainly on prevention and antibiotic treatment. Due to the limited protecti...

Claims

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Application Information

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IPC IPC(8): A61K31/353A61K36/82A61P31/04
Inventor 卢琴罗青平叶飞郭云清张腾飞张文婷邵华斌
Owner INST OF ANIMAL SCI & VETERINARY HUBEI ACADEMY OF AGRI SCI
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