Digestive tract drug delivery system

Abstract

The invention provides a digestive tract drug delivery system, which comprises a drug carrying clamp body and a clamp body release piece, wherein the drug carrying clamp body is used for carrying drugs, the drug carrying clamp body and the drugs are clamped on the designated part of the inner wall of a digestive tract together, the clamp body release piece is used for carrying the drug carrying clamp body and releasing the drug carrying clamp body after the drug carrying clamp body reaches the designated part, the clamp body release piece comprises a shape memory supporting head and a temperature conduction wire, the supporting legs of the shape memory supporting head are assembled on the clamping sheet portion of the drug carrying clamp body in an open state, the clamping sheet portion is opened by applying force to elastic clamping sheets on the two sides of the clamping sheet portion, and when the shape memory supporting head reaches a deformation temperature, the supporting legs are deformed into a contraction state from the open state, the clamping sheet portion loses supporting and is in a clamping state, and the system further comprises an in-vitro temperature control module used for transmitting energy needed for reaching the deformation temperature to the shape memory supporting head through the temperature conduction wire. According to the invention, a temperature control shape memory function material is introduced to achieve elastic release of a drug medicine carrying clamp body after reaching a diseased part, so that in-situ slow clamping of the diseased part is achieved, manpower intervention is avoided, and the success rate is increased.

Description

technical field [0001] The invention relates to the field of medical technology, in particular to an alimentary tract drug delivery system using temperature-controlled shape-memory functional materials. Background technique [0002] Common diseases of the gastrointestinal tract are inflammation, ulcers, tumors, etc., such as ulcerative colon or proctitis, etc. In addition to the most common oral or injection administration methods for the gastrointestinal tract, it also includes washing or direct administration of the diseased part Oral or injection administration is systemic administration. Although the operation is convenient, the drug dosage is large, the absorption of the lesion is poor, and the side effects are also large. The washing or direct administration of the lesion is local administration, because it is more targeted to the lesion. Sex, good absorption, and few side effects, but local administration requires professional medical personnel to operate, and the fre...

AI Technical Summary

Problems solved by technology

With the advancement of material technology, medical workers have successively developed smaller and safer or degradable drug carriers, and developed simpler operation methods, such as using small biological clips to pack simpler drug forms such as no outer packaging Medicines, layered capsules, etc. are fixed on the diseased part of the body, but because the small biological clamp device generally clamps the inner wall of the digestive tract, it is necessary for medical personnel to control the elasticity of the biological clamp by manually controlling the clamping device under the guidance of endoscopic equipment And release, and make the biological clamp accurately clamp the designated part of the inner wall of the digestive tract. This series of operations is greatly affected by the force exerted by the human hand during the operation, which brings great challenges to the medical staff. The success rate depends on the operator. experience of

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