Pure platelet-rich plasma manufacturing centrifugal system and manufacturing method thereof

Abstract

The invention belongs to the field of medical instruments, and particularly relates to a pure platelet-rich plasma manufacturing centrifugal system and a manufacturing method thereof. The system comprises a sterile syringe used for sampling; a centrifugal machine providing a centrifugal effect; a centrifugal sleeve of an inverted structure used in cooperation with the centrifugal machine; and a separator used for carrying out sample purification on the sterile syringe after centrifugation. The manufacturing method comprises the steps of sample preparation, primary centrifugation, purification and re-sampling, secondary centrifugation, final sampling and the like, wherein pure platelet-rich plasma with high purity is finally obtained. According to the system and the method provided by the invention, a conventional medical general syringe can be directly used for a closed centrifugal sleeve, so that the problem of contact with the outside in the transferring and centrifuging process is effectively solved, and the pollution risk in the PRP preparation process is reduced; and meanwhile, P-PRP is conveniently extracted, the purity is improved, and residual pollution is rejected.

Description

technical field [0001] The invention belongs to the field of medical devices, and in particular relates to a centrifuge sleeve device adapted to accommodate a universal syringe and applied to a centrifuge during the preparation and extraction of PRP, in particular to a centrifuge kit for producing leukocyte-depleted platelet-rich plasma and a production method thereof. Background technique [0002] Platelet-rich plasma (platelet-rich plasma, PRP) is an extract of autologous whole blood that contains high concentrations of platelets and growth factors. According to the concentration of leukocytes, PRP can be roughly divided into two categories: Leukocyte platelet-rich plasma (L-PRP) containing high concentrations of leukocytes and leukocyte-depleted platelet-rich plasma (Pure PRP) containing no or only low concentrations of leukocytes. platelet-rich plasma, P-PRP). [0003] Studies in recent years have shown that the concentrations of interleukin 1β (interleukin 1β, IL-1β) a...

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Problems solved by technology

[0007] The object of the present invention is to solve the above problems, to provide a centrifuge suit for making platelet-rich plasma without leukocytes and its production method, which can directly use a conventional medical general-purpose syringe for a closed centrifuge sleeve, effectively solving the problem of external contact during transfer and centrifugation. Contact problems, reduce the risk of contamination during the PRP preparation process, and at the same time facilitate the extraction of P-PRP, improve purity, and reject residual pollution

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