Modified natural melanin core-shell nanoparticles as well as preparation method and application thereof

Abstract

The invention discloses a modified natural melanin core-shell nanoparticle as well as a preparation method and application thereof, the center of the core-shell nanoparticle is a natural melanin nanoparticle, a layer of silicon dioxide is tightly wrapped outside melanin, and then a mesoporous silicon dioxide layer with a cavity structure is wrapped outside the layer of silicon dioxide. The mesoporous silicon dioxide layer has a wide mesoporous aperture range and a large specific surface area. The preparation method comprises the following steps: collecting melanin nanoparticles from an ink sac of cuttlefish, reacting the melanin nanoparticles with an alkaline / acidic catalyst and an organic silicon source in an aqueous solution to obtain dense silicon dioxide-coated melanin nanoparticles, dispersing the nanoparticles into an aqueous solution containing a template agent and a pore-enlarging agent, adding an aqueous solution of the organic silicon source and an alkaline biocatalyst, carrying out a water bath stirring reaction, dispersing the obtained precipitate into ethanol containing ammonium nitrate, and refluxing to obtain a product. The obtained product has good hydrophilicity and loading capacity, has high photothermal conversion efficiency, and can be widely applied to the photothermal conversion fields of seawater desalination, biological treatment and the like as a photothermal agent.

Description

technical field [0001] The invention belongs to the technical field of melanin modification, and in particular relates to a modified natural melanin core-shell nanoparticle and its preparation method and application. Background technique [0002] Natural melanin is a biological pigment formed by a series of chemical reactions of tyrosine or 3,4-dihydroxyphenylalanine, which widely exists in natural organisms. The ink sacs of cuttlefish contain a large amount of natural melanin. In the field of marine resources in our country, cuttlefish resources are abundant. The annual processing of discarded ink sacs causes a lot of waste of resources. The melanin nanoparticles in the ink sacs usually exist in the form of black aggregates. Due to It has interesting properties such as broad-spectrum light absorption, photothermal conversion, free radical scavenging, electron transfer and paramagnetism, and has been widely studied in the field of nanobiology. [0003] Melanin is highly hyd...

AI Technical Summary

Problems solved by technology

The invention wraps a thin layer of dense silica on the natural melanin nanoparticles, which is very beneficial to further grow mesoporous silica on it, so as to realize the modification of melanin by inorganic small molecules and solve the problem of hydrophilic long-chain The problem of secondary agglomeration easily caused by polymer modification of melanin nanoparticles

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