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Prediction model for non-invasive quantitative evaluation of postoperative concurrent pancreatic fistula risk before pancreatic resection

A prediction model and quantitative evaluation technology, applied in the field of medical imaging, can solve the problems of differences between observers, lack of preoperative prediction, and difficulty in quantifying results, and maximize the effectiveness and accuracy.

Pending Publication Date: 2022-01-18
ZHONGSHAN HOSPITAL FUDAN UNIV
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Problems solved by technology

However, at present, there is still no objective and effective index for the risk assessment of pancreatic fistula after pancreatectomy, and more often it relies on the experience judgment of clinicians, or the subjective evaluation of the texture of the pancreas by palpation of the pancreas during laparotomy. Judgment, not only prone to inter-observer differences, difficult to quantify results, but also lacks the possibility of preoperative prediction

Method used

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  • Prediction model for non-invasive quantitative evaluation of postoperative concurrent pancreatic fistula risk before pancreatic resection
  • Prediction model for non-invasive quantitative evaluation of postoperative concurrent pancreatic fistula risk before pancreatic resection

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Experimental program
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Embodiment

[0044] A. Acquisition of conventional ultrasound and ultrasound elasticity images of pancreatic lesions before operation:

[0045] Quantitative ultrasound elasticity analysis was performed on pancreatic lesions and pancreatic body parenchyma in patients. First, conventional two-dimensional ultrasound was used to evaluate internal echoes and color blood flow signals of pancreatic tumors. After the ultrasound image of the area to be observed is stabilized, select the best observation plane, select the ultrasonic shear wave elastography mode, place a 10mm×10mm elastic sampling frame in the pancreas area of ​​interest, and pay attention to avoiding the large blood vessels around the pancreas and the necrotic area inside the tumor . When the color in the elastic sampling frame is uniformly filled, it means that the image quality IQR of elastography is satisfactory, and the image is frozen for SWV (m / sec) measurement. The pancreatic lesion and pancreatic body parenchyma were measur...

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Abstract

The invention relates to a prediction model for non-invasive quantitative evaluation of postoperative concurrent pancreatic fistula risk before pancreatic resection, and belongs to the technical field of medical imaging. According to the invention, a real image obtained in clinical practice is put into an artificial intelligence end, and ultrasonic multi-mode and preoperative various pancreatic fistula related indexes are combined; the method also comprises deeply mining image omics characteristic information in an image by using an AI algorithm, comprehensively evaluating, screening, weighting and comprehensively calculating the image omics characteristic information, extracting useful information, and establishing a diagnosis and treatment model for artificial intelligence prediction of postoperative pancreatic fistula in combination with various preoperative characteristics of a patient and related laboratory examination and image examination results. Starting from ultrasonic elastic quantification, the problem that the pancreas texture cannot be objectively evaluated before a pancreas resection operation in the past is solved, and non-invasive quantification is conducted on the pancreas texture; meanwhile, an artificial intelligence machine learning method is introduced, the problem that a large amount of information cannot be processed in real time during manual image analysis is solved, and the effectiveness and accuracy of a prediction model are maximized.

Description

technical field [0001] The invention relates to a prediction model for non-invasive quantitative evaluation of the risk of pancreatic fistula after pancreatectomy, belonging to the technical field of medical imaging. Background technique [0002] Pancreatic fistula (Pancreatic Fistula) is one of the most serious complications after acute pancreatitis, chronic pancreatitis, abdominal surgery (especially pancreatectomy) and abdominal trauma. Pancreatic juice leaving the normal outflow tract can accumulate in the abdominal cavity and cause necrosis of surrounding tissues, and then secondary infection. Infection can accelerate the activation of pancreatic enzymes and strengthen the digestion and corrosion of pancreatic juice. The erosion of the gastrointestinal tract by pancreatic juice can cause bleeding and internal fistula in the stomach, small intestine, colon, etc., and if the blood vessels are eroded, it can cause fatal massive hemorrhage. For patients with poor general c...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/30G16H50/50G16H50/70G06N20/00A61B8/00
CPCG16H50/30G16H50/50G16H50/70G06N20/00A61B8/485A61B8/5215A61B8/5223
Inventor 董怡楼文晖王文平王单松张磊曹佳颖范培丽
Owner ZHONGSHAN HOSPITAL FUDAN UNIV
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