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Plant anti-dandruff antipruritic agent as well as preparation method and application thereof

An anti-dandruff and anti-itching agent, plant technology, applied in the field of daily chemical products, can solve the problem of skin irritation of the composition, and achieve high-efficiency antibacterial and anti-inflammatory effects with high safety

Active Publication Date: 2021-12-28
广州锦同生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, although the prior art reports that Chinese medicine components are used for anti-dandruff and antipruritic, the addition of other Chinese medicine ingredients, western medicine ingredients, preservatives and / or surfactants may cause the composition to produce additional irritation to the skin sex

Method used

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  • Plant anti-dandruff antipruritic agent as well as preparation method and application thereof
  • Plant anti-dandruff antipruritic agent as well as preparation method and application thereof
  • Plant anti-dandruff antipruritic agent as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The preparation method of Centella asiatica extract: dry and pulverize Centella asiatica, add 10 times the volume of an 80% ethanol solution to reflux for extraction for 2 hours, filter the extract to collect the filtrate to obtain an alcohol extract, and recover ethanol under reduced pressure to nothing Alcoholic taste, that is, it contains more than 20 wt% of Centella asiatica.

[0027] The preparation method of Baiwei extract: dry Baiwei at 40-50°C, crush and pass through a 40-mesh sieve, take the powder under the sieve, add ethanol with a volume percentage concentration of 30% 10 times the weight of the Baiwei to extract, The extraction temperature is 50°C, the extraction time is 3 hours, and the alcohol extract is obtained by filtration, and the ethanol is recovered under reduced pressure until there is no alcohol smell, and it contains more than 0.3 wt% of astragalus.

[0028] Gentiana extract and loquat leaf extract: prepared according to the same method as extra...

Embodiment 2

[0032] Take 100g of Baiwei extract, 25g of Centella asiatica extract, 15g of gentian extract and 15g of loquat leaf extract, and disperse them in a mixed solvent composed of water and propylene glycol, wherein the amount of the mixed solvent is 300g, and the composition is 200g of water+ 100g of propylene glycol, mix well to get.

Embodiment 3

[0034] Take 120g of Baiwei extract, 20g of Centella asiatica extract, 10g of gentian extract and 10g of loquat leaf extract, and disperse them in a mixed solvent composed of water and propylene glycol, wherein the amount of the mixed solvent is 300g, and the composition is 200g of water+ 100g of propylene glycol, mix well to get.

[0035] Preparation of the composition for the control group:

[0036] Control group 1: same as above-mentioned embodiment 1, difference is not to add Centella asiatica extract;

[0037] Control group 2: the same as the above-mentioned embodiment 1, the difference is that the gentian extract is not added;

[0038] Control group 3: the same as the above-mentioned embodiment 1, the difference is that no loquat leaf extract is added.

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Abstract

The invention relates to a plant anti-dandruff antipruritic agent as well as a preparation method and application thereof. The plant anti-dandruff antipruritic agent only comprises the following active ingredients in parts by weight: 100-150 parts of a cynanchum atratum extract, 15-25 parts of a centella asiatica extract, 8-12 parts of a radix gentianae extract and 8-12 parts of a folium eriobotryae extract. According to the plant anti-dandruff antipruritic agent, through the synergistic effect of all the components, the plant anti-dandruff antipruritic agent has efficient bacteriostatic and anti-inflammatory effects, can achieve the purposes of removing dandruff and relieving itching, and has the advantages of being natural, mild, non-irritant and high in safety.

Description

technical field [0001] The invention relates to the field of daily chemical products, in particular to a plant antidandruff and antipruritic agent and its preparation method and application. Background technique [0002] Dandruff occurs because the scalp is constantly undergoing metabolism. Once the metabolism is abnormal, excessive scalp cells will peel off and become a seedless, lifeless cuticle, causing dandruff. A large number of studies have proved that Malassezia is closely related to the generation and severity of dandruff, and the massive reproduction of Malassezia on the scalp causes the excessive proliferation of the stratum corneum of the scalp, which promotes the abnormality of the stratum corneum cells in the form of white or gray scales Come off, this exfoliated scale is dandruff. Malassezia is a single-celled fungus of the yeast type, which is found on everyone's head and lives by "sucking" scalp oil. With a healthy scalp, Malassezia and scalp susceptibility...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61Q5/02A61Q5/00A61Q17/00A61P17/04A61P29/00
CPCA61K8/9789A61Q5/02A61Q5/006A61Q17/005A61P17/04A61P29/00A61K2800/592Y02A50/30
Inventor 张庆孔令超
Owner 广州锦同生物科技有限公司
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