Photomultiplier tube assembly, analysis device and optical calibration method thereof

Abstract

The invention discloses a photomultiplier tube assembly, an analysis device and an optical calibration method thereof. The photomultiplier tube assembly comprises a photomultiplier tube body, a reference device and an electric signal acquisition device, the reference device comprises a reference light source, a photoelectric detector and a light guide part, and the reference light source and the photoelectric detector are arranged at an interval; the light guide part is provided with an input end, a first output end and a second output end, the input end is connected with the reference light source, the first output end is connected with the photoelectric detector, and the second output end corresponds to the photomultiplier tube body; and the photomultiplier tube body and the photoelectric detector are electrically connected with the electric signal acquisition device respectively. According to the photomultiplier tube assembly, the reference module and the photomultiplier tube body are integrated, the reference module and the photomultiplier tube body can be installed in an analysis device together, the photomultiplier tube assembly does not need to be detached from the analysis device for detection and calibration, and detection and calibration can be completed through the photomultiplier tube assembly.

Description

technical field [0001] The invention relates to the technical field of chemical analyzers, in particular to a photomultiplier tube assembly, an analysis device and an optical calibration method thereof. Background technique [0002] The chemiluminescent immunoassay analyzer uses chemiluminescent substances to form an excited state intermediate through the catalysis of the catalyst and the oxidation of the oxidant. When the excited state intermediate returns to the stable ground state, it emits photons at the same time, and uses the luminescent signal to measure The instrument measures the light quantum yield. The immune reaction system is to directly label the luminescent substance (excited state intermediate generated under the excitation of the reactant) on the antigen (chemiluminescence immunoassay) or antibody (immunochemiluminescence assay), or the enzyme acts on the luminescent substrate. [0003] The core detection device in the chemiluminescent immunoassay instrumen...

AI Technical Summary

Problems solved by technology

[0004] The photomultiplier tube is a photoelectric sensor with very high sensitivity, but in actual use, once the photomultiplier tube fails, the detection result will be abnormal, resulting in misdiagnosis, so it is necessary to regularly test and calibrate the performance of the photomultiplier tube

In the existing chemiluminescence immunoassay analyzer, the common method is to disassemble the photomultiplier tube from the chemiluminescence immunoassay analyzer, and then perform detection and calibration. This method is complicated and time-consuming, and it is easy to cause the photomultiplier tube damage

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