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Mirnas as biomarkers for parkinson's syndrome

A technology for Parkinson's and syndromes, applied in the direction of microbial determination/testing, biological testing, biomaterial analysis, etc., can solve problems such as unmet clinical needs

Pending Publication Date: 2021-09-28
HUMMINGBIRD DIAGNOSTICS GMBH
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Therefore, there remains an unmet clinical need for an efficient, simple, reliable and accurate diagnostic test for PD and Parkinson's disease and for the differential diagnosis between PD and Parkinson's disease

Method used

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  • Mirnas as biomarkers for parkinson's syndrome
  • Mirnas as biomarkers for parkinson's syndrome
  • Mirnas as biomarkers for parkinson's syndrome

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Embodiment approach

[0120] There are currently no standard blood or laboratory tests that have been shown to help diagnose Parkinson syndrome (PS), Parkinson disease (PD), or Parkinsonism or to help differentiate PD from Parkinsonism. Therefore, diagnosis is based on history and neurologic examination. Parkinsonism (PS), PD or Parkinsonism can be difficult to diagnose accurately. Doctors may sometimes order brain scans or lab tests to rule out other disorders. Currently, there is no cure for Parkinson's Syndrome (PS), PD, or Parkinson's disease, but a variety of medications can provide significant symptom relief. To overcome current barriers to better clinical trial design by improving the assessment of Parkinson's disease or Parkinson's progression across the disease spectrum, new diagnostic and progression biomarkers in PD or Parkinson's There is a pressing unmet need. The inventors identified miRNAs as biomarkers for Parkinson syndrome (PS), Parkinson disease (PD) and Parkinsonism. They al...

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Abstract

The present invention relates to methods for diagnosing a Parkinson's syndrome (PS), Parkinson's disease (PD), or Parkinsonism in an individual. Further, the present invention relates to a method for differential diagnosing between PD and Parkinsonism. Furthermore, the present invention relates to methods for monitoring the course of a Parkinson's syndrome, Parkinson's disease (PD), or Parkinsonism in an individual. In addition, the present invention relates to kits suitable to carry out the above described methods.

Description

technical field [0001] The present invention relates to methods for diagnosing Parkinson's syndrome (PS), Parkinson's disease (PD) or Parkinsonism in an individual. Furthermore, the present invention relates to a method for differential diagnosis between PD and Parkinson's disease. Furthermore, the present invention relates to methods for monitoring Parkinson's syndrome, Parkinson's disease (PD) or the course of Parkinson's disease in an individual. Furthermore, the invention relates to kits suitable for carrying out the methods described above. Background technique [0002] Molecular diagnostics are gaining in importance. It has entered the clinical diagnosis of disease (especially the detection of infectious pathogens, detection of genomic mutations, detection of diseased cells and identification of risk factors for disease susceptibility). In particular, nucleic acid analysis opens up very promising new possibilities for the research and diagnosis of diseases by determ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/6883G01N33/53
CPCC12Q1/6883C12Q2600/178G01N33/5308G01N2800/2835C12Q2600/112C12Q2600/158
Inventor 安德烈亚斯·凯勒布鲁诺·施泰因克劳斯
Owner HUMMINGBIRD DIAGNOSTICS GMBH
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