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Tea pigment composition for treating cardiovascular and cerebrovascular diseases and preparation method thereof

A technology for cardiovascular and cerebrovascular diseases and compositions, which is applied in the field of tea pigment compositions and preparations, can solve the problem of further improvement of the anti-oxidative and anti-inflammatory effects of anti-atherosclerosis treatment, unclear anti-atherosclerosis curative effect, Poor clinical adaptability and other problems, to achieve the effect of improving hemorheology, improving treatment effect, and high inclusion rate

Active Publication Date: 2021-09-24
生命之花(北京)健康管理有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Claims to have the effect of lowering blood sugar, blood pressure or blood lipid, but the prescription is complicated, the clinical adaptability is poor, and the curative effect on anti-atherosclerosis is not clear
[0006] Chinese invention patent CN101461896B discloses a traditional Chinese medicine composition for assisting in lowering blood fat and a preparation method thereof. The composition is composed of 4 g of ganoderma lucidum, 2 g of American ginseng, 3 g of notoginseng, 4 g of kudzu root, 2 g of hawthorn, 2 g of Polygonatum and 2 g of Polygonatum Polygonatum. The method has Certain blood lipid-lowering effects, but the antioxidant and anti-inflammatory effects in anti-atherosclerosis treatment need to be further improved

Method used

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  • Tea pigment composition for treating cardiovascular and cerebrovascular diseases and preparation method thereof
  • Tea pigment composition for treating cardiovascular and cerebrovascular diseases and preparation method thereof
  • Tea pigment composition for treating cardiovascular and cerebrovascular diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A tea pigment composition for treating cardiovascular and cerebrovascular diseases. The raw material components are as follows: 5 parts of tea pigment, 5 parts of Cnidium, 10 parts of Panax notoginseng, 5 parts of American ginseng, 10 parts of Eupatorium, 10 parts of Polygonatum odoratum, and 5 parts of Cornus officinalis , 10 parts of Ophiopogon japonicus and 10 parts of Gualou.

[0032] The preparation method is as follows:

[0033] (1) Add 8 times the amount of water to extract the volatile oil from Cnidium Fructus Cnidii, Trichosanthes, American Ginseng and Polygonatum Polygonatum for 3 hours, and filter to obtain the volatile oil, filtrate a and filter residue a; add water to β-cyclodextrin to make 0.5g / mL β-cyclodextrin Aqueous solution, mix volatile oil with β-cyclodextrin solution, stir magnetically at 200r / min at a constant temperature of 55°C for 1h, cool, filter with suction, and dry to obtain volatile oil clathrate; the mass ratio of volatile oil to β-cyclod...

Embodiment 2

[0038] A tea pigment composition for treating cardiovascular and cerebrovascular diseases. The raw material components are as follows: 10 parts of tea pigment, 8 parts of Cnidium, 15 parts of Panax notoginseng, 10 parts of American ginseng, 15 parts of Eupatorium, 15 parts of Polygonatum odoratum, and 8 parts of Cornus officinalis , 15 parts of Ophiopogon japonicus and 15 parts of Gualou.

[0039] The preparation method is as follows:

[0040](1) Add 10 times the amount of water to extract the volatile oil from Cnidium Fructus Cnidii, Trichosanthes, American Ginseng and Polygonatum Polygonatum for 5 hours, and filter to obtain the volatile oil, filtrate a and filter residue a; add water to β-cyclodextrin to make 0.5g / mL β-cyclodextrin Aqueous solution, mix volatile oil with β-cyclodextrin solution, stir magnetically at 200r / min at a constant temperature of 65°C for 3h, cool, filter with suction, and dry to obtain volatile oil clathrate; the mass ratio of volatile oil to β-cycl...

Embodiment 3

[0045] A tea pigment composition for treating cardiovascular and cerebrovascular diseases, the raw material components are as follows: 8 parts of tea pigment, 5 parts of Cnidium monnieri, 15 parts of Panax notoginseng, 8 parts of American ginseng, 12 parts of Eupatorium, 10 parts of Polygonatum odoratum, and 8 parts of Cornus officinalis , 10 parts of Ophiopogon japonicus and 12 parts of Gualou.

[0046] The preparation method is as follows:

[0047] (1) Add 8 times the amount of water to extract the volatile oil from Cnidium Fructus Cnidii, Trichosanthes, American Ginseng and Polygonatum Polygonatum for 3 hours, and filter to obtain the volatile oil, filtrate a and filter residue a; add water to β-cyclodextrin to make 0.5g / mL β-cyclodextrin Aqueous solution, mix volatile oil with β-cyclodextrin solution, stir magnetically at 200r / min at a constant temperature of 60°C for 2h, cool, filter with suction, and dry to obtain volatile oil clathrate; the mass ratio of volatile oil to...

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Abstract

The invention belongs to the field of traditional Chinese medicine treatment for treating cardiovascular and cerebrovascular diseases, and particularly relates to a tea pigment composition for treating cardiovascular and cerebrovascular diseases as well as a preparation method and application thereof. The composition is prepared from the following raw material components of 5 to 10 parts of tea pigment, 5 to 10 parts of fructus cnidii, 10 to 15 parts of radix notoginseng, 5 to 10 parts of American ginseng, 10 to 15 parts of herba lycopi, 10 to 15 parts of radix polygonati officinalis, 5 to 10 parts of fructus corni, 10 to 15 parts of radix ophiopogonis and 10 to 15 parts of fructus trichosanthis. The preparation method comprises the following steps of extracting volatile oil from fructus cnidii, fructus trichosanthis, American ginseng and radix polygonati officinalis, carrying out alcohol extraction and purification on decoction dregs, radix notoginseng, herba lycopi, fructus corni and radix ophiopogonis, and finally mixing the extracts with the tea pigment and the auxiliary materials. All the medicines are organically compatible, and the composition has relatively good effects of regulating blood fat and improving hematorheology.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine treatment, and in particular relates to a tea pigment composition for treating cardiovascular and cerebrovascular diseases, a preparation method and application thereof. Background technique [0002] Cardiovascular and cerebrovascular diseases are collectively referred to as diseases of the heart and cerebrovascular diseases. It generally refers to ischemic or hemorrhagic diseases of the heart, brain, and systemic tissues caused by hyperlipidemia, blood viscosity, atherosclerosis, and high blood pressure. The etiology and pathogenesis of anti-atherosclerosis (AS) are extremely complex, and the exact etiology and pathogenesis have not been determined so far. The recognized risk factors and pathogenesis are as follows: (1) lipid metabolism disorder; serum cholesterol The increase of α was positively correlated with the occurrence of AS. With the in-depth research on lipoproteins, it is ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K47/69A61P3/06A61P9/00A61P9/10A61K36/234A61K36/258
CPCA61K36/82A61K36/234A61K36/258A61K36/53A61K36/8969A61K36/40A61K36/8968A61K36/428A61K47/6951A61P9/10A61P9/00A61P3/06A61K2236/331A61K2236/333A61K2236/55A61K2300/00Y02A50/30
Inventor 郑涵席宾刘春颖
Owner 生命之花(北京)健康管理有限公司
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