Chloramphenicol efficient degrading bacterium, efficient degrading bacterium agent and application thereof

Abstract

The invention provides a chloramphenicol efficient degrading bacterium, an efficient degrading bacterium agent and application thereof, and belongs to the technical field of biodegradation. The classification name of the chloramphenicol efficient degrading bacterium is Shewanella algae, the code is SA-cd1, and the chloramphenicol efficient degrading bacterium has been preserved in the China General Microbiological Culture Collection Center with the preservation number being CGMCC No.21690. The strain is separated and screened from paphia undulata, and can be prepared into the bacterium agent to be applied to chloramphenicol degradation. The degrading bacterium is extremely high in chloramphenicol degradation efficiency and wide in degradation condition, metabolites of the degrading bacterium can be independently and rapidly degraded, growth and metabolism of thalli do not need to be depended on, and the application advantages and value are large.

Description

technical field [0001] The invention relates to the technical field of biodegradation, in particular to a chloramphenicol high-efficiency degradation bacterium, a high-efficiency degradation bacterium agent and applications thereof. Background technique [0002] Chloramphenicol is a highly efficient and broad-spectrum chloronitroaromatic antibiotic. Since its large-scale artificial synthesis in 1949, it has been widely used in human medicine, livestock and poultry and aquatic veterinary medicine and other fields. However, researchers have found that chloramphenicol can damage human hematopoietic function and cause aplastic anemia, and has potential carcinogenicity and genotoxicity to humans. The abuse of chloramphenicol will also lead to the occurrence and spread of drug-resistant bacteria and their resistance genes, which will have a serious impact on the ecological environment. Therefore, my country banned the use of chloramphenicol in food-borne animals in 2002, but beca...

AI Technical Summary

Problems solved by technology

[0004] In recent years, people have obtained some microbial communities or bacterial strains with the function of degrading chloramphenicol through domestication, isolation and screening. However, the degradation conditions of these bacterial strains or bacterial communities are harsh and serious. It depends on the growth conditions of the bacteria, and the degradation time is long and the degradation efficiency is low, so it is difficult to obtain wide application

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