Composition, preparation method and application of composition in treatment of bacterial diseases

Abstract

The invention discloses a composition. The composition comprises lactoferrin and bacteriophage, wherein the bacteriophage is used for cracking infected bacteria, timely removing harmful bacteria in a body and quickly and efficiently recovering a sterile environment in the body; the lactoferrin can better play a role in improving the immunity in the body without the harmful bacteria, so that discomfort such as inflammation, ulcer, redness and swelling, abscess and the like caused by bacterial infection can be quickly and efficiently eliminated, and the body is recovered to be healthy. The bacteriophage and the lactoferrin are compounded, the bacteriophage can be attached to lactoferrin molecules, and the bacteriophage is prevented from being inactivated by resistance factors by means of 'shielding' of the lactoferrin and successfully reaches the focus of infection. Besides, the lactoferrin is used as a bactericide, can be subjected to non-specific binding with surface molecules of the bacteria and can quickly and accurately locate the harmful bacteria, so that accurate infection of the bacteriophage on the harmful bacteria is helped.

Description

technical field [0001] The invention provides a composition, a preparation method and its application in treating bacterial diseases, which belong to the technical field of microbial application. Background technique [0002] Bacterial infection can cause a variety of diseases in humans and animals, such as human enteritis caused by Escherichia, vomiting and diarrhea caused by Vibrio cholerae, etc. Once infected with bacteria, antibiotic therapy is mostly used for sterilization clinically. However, with the use of antibiotics, more and more bacteria have developed resistance. The result is bacteria that are resistant to many antibiotics, even superbugs. This will inevitably lead to an infection that cannot be treated. Therefore, it is an urgent problem to be solved to find a kind of therapeutic drug or therapeutic method that can effectively kill bacteria without producing antibiotic resistance instead of antibiotics. [0003] A phage is a virus that infects microorganis...

AI Technical Summary

Problems solved by technology

Although the above reports can quickly relieve bacterial infection in a short period of time, various inflammations, ulcers, abscesses and other symptoms caused by bacterial infection cannot be effectively treated

Moreover, the body after bacterial infection, although the bacteria are lysed by phages, the immune system of the body is destroyed due to the invasion of bacteria, which is not conducive to the recovery of complications of bacterial infection.

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