Medicine for treating oral ulcer and its preparing process

A technique for treating oral ulcers and oral ulcers, which is applied in the field of application of total flavonoids in the preparation of drugs for treating oral ulcers. good taste effect

Inactive Publication Date: 2003-12-10
陕西白鹿制药股份有限公司
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  • Abstract
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  • Claims
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Problems solved by technology

Guangxi Science 1999, 6 (3) discloses the application of refined total flavonoids of S. denticulata in pharmacological experiments such as anti-platelet aggregation, anti-thrombosis, lowering blood fat and anti-oxidation, but there is no report on the application of drugs for the treatment of oral ulcers

Method used

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Examples

Experimental program
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Effect test

Embodiment

[0009] Example: Preparation of Kouchuangning Buccal Tablets

[0010] 1. Take 10kg of the raw material Snake-toothed Grapes and add 100kg of water at 90-95°C, heat preservation and extraction for 0.5-1 hour, and press filter; add 80kg of medicinal residues and add 90-95°C water for heat preservation and extraction for 0.5-1 hour, press filtration, and combine The water extract is concentrated under reduced pressure to a relative density of 1.05-1.08 (60-70°C thermal measurement), placed at a temperature below 4°C for 24 hours, filtered with suction, dried, and finely ground to obtain 1.5kg of crude total flavonoids;

[0011] 2. Add 10000ml of 95% ethanol to 1kg of crude total flavonoids, add 200g of activated carbon, heat and reflux for 0.5 hours, filter with suction, concentrate the filtrate under reduced pressure to about 2500ml, leave it at room temperature for 24 hours, after crystallization, filter with suction, and dry to obtain Total flavonoids of Snake-toothed Grape 0.6...

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Abstract

A medicine for treating oral ulcer is prepared from the stem and leaf of amur ampelopsis through leaching, press filtering, concentrating, refining to obtain general flavone of amur ampelopsis, adding additives and tabletting. Its advantages are high curative effect (96.67% of total effective rate) and no toxic by-effect.

Description

technical field [0001] The invention relates to the application of the total flavonoids of S. japonica in the preparation of medicine for treating oral ulcer. Background technique [0002] Oral ulcer is a frequently-occurring disease. Traditional Chinese medicine believes that it is mainly caused by accumulated heat in the heart and spleen, deficiency of yin and hyperactivity of fire. The existing medicine for treating oral ulcer is to take anti-inflammatory drugs or oral anti-inflammatory tablets, but the curative effect is not very significant. Guangxi Science 1999, 6 (3) discloses the application of the refined total flavonoids of Grape dentata in pharmacological experiments such as anti-platelet aggregation, anti-thrombosis, lowering blood fat and anti-oxidation, but there is no report on the application of the drug in the treatment of oral ulcers . Contents of the invention [0003] The object of the present inv...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/352A61P1/02
Inventor 陈立峰王实强蔡光先王晓洪
Owner 陕西白鹿制药股份有限公司
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