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Traditional Chinese medicine composition for treating and/or preventing fish streptococcicosis and preparation method thereof

A streptococcal disease and composition technology, applied in the field of biomedicine, can solve the problems of lack of theoretical guidance and the inability to truly exert the curative effect of drugs, and achieve the effects of high concentration, convenient mixing application, and small volume

Inactive Publication Date: 2021-06-11
GUANGDONG PHARMA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although in recent years, natural plants such as Chinese herbal medicines or their extracts have also begun to be used in the prevention and treatment of fish streptococcosis, but there is a lack of certain theoretical and ideological guidance. , can not really exert the efficacy of the drug

Method used

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  • Traditional Chinese medicine composition for treating and/or preventing fish streptococcicosis and preparation method thereof
  • Traditional Chinese medicine composition for treating and/or preventing fish streptococcicosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1 A kind of Chinese medicine composition for the treatment and / or prevention of fish streptococcosis

[0030] The traditional Chinese medicine composition comprises the following components and parts by weight: 40 parts by weight of oregano, 20 parts by weight of Scutellaria baicalensis, 20 parts by weight of Artemisia annua, 20 parts by weight of Citrus aurantium, 10 parts by weight of dried ginger, 30 parts by weight of thyme, 2 parts by weight of the solubilizer; the solubilizer is composed of polysorbate 20, isooctyl polyoxyethylene ether, and lysolecithin in a weight ratio of 3:3:2.

[0031] The preparation method of the traditional Chinese medicine composition comprises the following steps:

[0032] S1, pulverize oregano, skullcap, artemisia annua, citrus aurantium, dried ginger, thyme into coarse powder, add 8 to 20 times by weight of water, soak for 0.5 to 2 hours, extract by steam distillation for 4 to 12 hours, and collect them respectively Extract...

Embodiment 2

[0037] Embodiment 2 A kind of Chinese medicine composition for the treatment and / or prevention of fish streptococcosis

[0038] The traditional Chinese medicine composition comprises the following components and parts by weight: 80 parts by weight of oregano, 50 parts by weight of Scutellaria baicalensis, 60 parts by weight of Artemisia annua, 50 parts by weight of Citrus aurantium, 30 parts by weight of dried ginger, 70 parts by weight of thyme, 8 parts by weight of the solubilizer; the solubilizer is composed of polysorbate 20 and Maize 49 in a weight ratio of 5:3.

[0039] The preparation method of the traditional Chinese medicine composition comprises the following steps:

[0040] S1, Oregano, Scutellaria, Artemisia annua, Citrus aurantium, dried ginger, thyme are pulverized into coarse powder, add 20 times by weight of water, soak for 2 hours, extract by steam distillation for 12 hours, collect extract, essential oil, pure The medicinal residues are stored for later use; t...

Embodiment 3

[0045] Embodiment 3 A kind of Chinese medicine composition for the treatment and / or prevention of fish streptococcosis

[0046] The traditional Chinese medicine composition comprises the following components and parts by weight: 60 parts by weight of oregano, 40 parts by weight of Scutellaria baicalensis, 35 parts by weight of Artemisia annua, 35 parts by weight of Citrus aurantium, 20 parts by weight of dried ginger, 50 parts by weight of thyme, 5 parts by weight of the solubilizer; the solubilizer is composed of laureth, polysorbate 85, Mizre 52 and lysolecithin in a weight ratio of 1:2:1:3.

[0047] The preparation method of the traditional Chinese medicine composition comprises the following steps:

[0048] S1, Oregano, Scutellaria baicalensis, Artemisia annua, Citrus aurantium, dried ginger, thyme are pulverized into coarse powder, add 12 times by weight of water, soak for 1.2 hours, extract by steam distillation for 7 hours, collect extract, essential oil, pure The medi...

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Abstract

The invention belongs to the field of biological medicine, and particularly relates to a traditional Chinese medicine composition for treating and / or preventing fish streptococcicosis and a preparation method and application thereof. The traditional Chinese medicine composition provided by the invention comprises the following components in parts by weight: 40-80 parts of origanum vulgare, 20-50 parts of scutellaria baicalensis, 20-60 parts of artemisia apiacea, 20-50 parts of fructus aurantii, 10-30 parts of rhizoma zingiberis, 30-70 parts of thyme and 2-8 parts of a solubilizer. The traditional Chinese medicine composition provided by the invention does not need to be independently added with a preservative, meets the requirements of greenness, naturalness, safety and health, has a strong bactericidal effect, is prepared into ointment, has the characteristics of high concentration, small volume, small dosage and the like, can ensure the effectiveness and uniformity of medicines, and is convenient for farmers to mix and apply.

Description

technical field [0001] The invention belongs to the field of biomedicine, and in particular relates to a traditional Chinese medicine composition for treating and / or preventing fish streptococcosis and a preparation method thereof. Background technique [0002] Streptococcus (Streptococcus) is a gram-positive bacteria of the genus Streptococcus, which can cause zoonotic disease; the pathogens of fish infection mainly include Streptococcus iniae and Streptococcus agalactiae (Streptococcusagalactiae). Fish streptococcosis is an infectious disease caused by infection of fish with Streptococcus or Lactococcus bacteria. Streptococcus infection is the most prevalent. It occurs in major fish farming countries on all continents of the world, and endangers various marine and fresh water. Fish, common symptoms include stray roaming around the pool, intermittent spiral or swirling swimming, unbalanced swimming posture, decreased feeding, unilateral or bilateral proptosis, redness on th...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K47/26A61K47/24A61K47/10A61K47/14A61P31/04
CPCA61K36/53A61K36/539A61K36/282A61K36/752A61K36/9068A61K47/26A61K47/24A61K47/10A61K47/14A61P31/04A61K2236/331A61K2236/51A61K2236/333A61K2236/39A61K2300/00
Inventor 蔡延渠
Owner GUANGDONG PHARMA UNIV
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