A kind of Bifidobacterium breve and its application in the preparation of non-alcoholic fatty liver functional drink

A bifidobacterium breve, non-alcoholic technology, applied in the field of biomedical processing, can solve problems such as difficult to achieve recurrence risk, achieve the effects of good efficacy and taste, improve lipid metabolism, and enhance regulatory functions

Active Publication Date: 2022-05-20
SYNBIOTECH BIOTECHNOLOGY YANGZHOU CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, for patients with obesity, hyperlipidemia, and diabetes, non-drug measures such as adjusting diet and rest and strengthening exercise are the main ways to prevent non-alcoholic fatty liver disease. Big

Method used

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  • A kind of Bifidobacterium breve and its application in the preparation of non-alcoholic fatty liver functional drink
  • A kind of Bifidobacterium breve and its application in the preparation of non-alcoholic fatty liver functional drink

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] 1) Preparation of fermentation substrate:

[0044] Skim milk powder 8g; Isomaltooligosaccharide syrup 5g; Fructooligosaccharide 1g; Galacto-oligosaccharide 2g; Food additive 1g; Replenish water to 100g.

[0045] 2) Sterilization: 70°C, 30min.

[0046] 3) Cooling: Cool to 37°C

[0047] 4) Inoculation: Inoculate Bifidobacterium breve BR18 so that the original number of bacteria is 1.0×10 4 cfu / ml.

[0048] 5) Fermentation: the fermentation temperature was 45°C and the time was 12h.

[0049] 6) Sterilization: 80℃, 5min.

[0050] 7) Filling.

Embodiment 2

[0052] 1) Preparation of fermentation substrate:

[0053] Skim milk powder 10g; Isomaltooligosaccharide syrup 6g; fructooligosaccharide 2g; galactooligosaccharide 3g; food additive 1g; water to 100g.

[0054] 2) Sterilization: 80°C, 25min.

[0055] 3) Cooling: Cool to 40°C

[0056] 4) Inoculation: Inoculate Bifidobacterium breve BR18 so that the original number of bacteria is 1.0×10 4 cfu / ml.

[0057] 5) Fermentation: the fermentation temperature was 40°C and the time was 18h.

[0058] 6) Sterilization: 85℃, 4min.

[0059] 7) Filling.

Embodiment 3

[0061] ) Preparation of fermentation substrate:

[0062] Skim milk powder 12g; Isomaltooligosaccharide syrup 6g; Oligofructose 3g; Galacto-oligosaccharide 2g; Food additives 2g;

[0063] 2) Sterilization: 85°C, 20min.

[0064] 3) Cooling: Cool to 40°C

[0065] 4) Inoculation: Inoculate Bifidobacterium breve BR18 so that the original number of bacteria is 1.0×10 5 cfu / ml.

[0066] 5) Fermentation: The fermentation temperature was 38°C and the time was 20h.

[0067] 6) Sterilization: 90℃, 3min.

[0068] 7) Filling.

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Abstract

The invention relates to a bifidobacterium breve and its application in the preparation of functional drinks capable of preventing non-alcoholic fatty liver. The Bifidobacterium breve is preserved in the General Microbiology Center of China Committee for Culture Collection of Microorganisms, and the preservation number is CGMCC NO.19430. The functional drink prepared by using the bifidobacterium breve can improve the homeostasis of intestinal flora and adjust fat metabolism, thereby having a good preventive effect on fatty liver lesions.

Description

technical field [0001] The invention relates to a Bifidobacterium breve and its application in the preparation of a functional beverage with the prevention of non-alcoholic fatty liver. It belongs to the field of biomedical processing technology. Background technique [0002] Fatty liver is a common liver pathological change disease, usually refers to excessive accumulation of fat in liver cells. Fatty liver disease has become the second largest liver disease after viral hepatitis. With the increasing incidence, the age of onset is gradually getting younger. Fatty liver is generally divided into two categories: alcoholic fatty liver and non-alcoholic fatty liver. Experimental data show that drinking more than 80 to 160 grams per day increases the incidence of alcoholic fatty liver disease by 5 to 25 times. Non-alcoholic fatty liver disease has become the most common chronic liver disease in the world. Long-term sedentary lifestyle and unhealthy eating habits lead to obesi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/20A23C9/123A61K35/745A61P1/16C12R1/01
CPCA23C9/1234A61K35/745A61P1/16A23V2400/519Y02A50/30
Inventor 许慈雪杨锁华姜益军杨阳王霞
Owner SYNBIOTECH BIOTECHNOLOGY YANGZHOU CO LTD
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