Microfauna tail fixing device for tail suspension test

Abstract

The invention discloses a microfauna tail fixing device for a tail suspension test, which comprises a box body and further comprises a partition plate for blocking the visual field of an experimentalmouse, the partition plate can be transversely inserted into the box body to divide the interior of the box body into an upper space and a lower space, and a through hole for the tail of the experimental mouse to pass through is formed in the middle of the partition plate; a microfauna tail fixator is arranged in the upper space of the partition plate, the microfauna tail fixator is fixed to the box body through two opposite supports, and the center line of the microfauna tail fixator coincides with the center line of the through hole; the microfauna tail fixator comprises an annular sleeve, aflexible protective layer is arranged on the inner side of the annular sleeve, the annular sleeve comprises a first port and a second port which are detachable, and when the tail of the experimentalmicrofauna passes through the through hole of the partition plate, the first port and the second port are closed so as to fix the tail of the experimental mouse; and a camera device is arranged at thebottom of the box body and is used for collecting video images of the laboratory mouse when the tail part of the laboratory mouse is fixed.

Description

technical field [0001] The present application relates to the technical field of tail suspension testing, in particular to a miniature animal tail fixing device for tail suspension testing. Background technique [0002] When performing tail suspension experiments on miniature animals (such as experimental rats) to check whether they suffer from depression, it is necessary to suspend the tail of the miniature animals for six minutes for observation. During the suspension process, the mice do not struggle violently and are relatively quiet Those with depression tendencies, and vice versa without depression tendencies. The existing miniature animal tail suspension method mainly uses rope ligation or ordinary clips to directly suspend the miniature animal tail. But because the miniature animal tail is conical, the root is thick, and the end is thin, the suspension rope needs to be fixed on the end of the miniature animal tail during suspension. When the weight of the mouse is ...

AI Technical Summary

Problems solved by technology

If the rope is tied too tightly, or the clip is over-clamped, it will cause: skin degloving injury of the tail of the miniature animal, severed tail of the miniature animal, ischemia and necrosis of the tail of the miniature animal, and the experiment cannot be continued

In addition, the results of the experiment can be disturbed by the pain of the tail of the miniature animal

In large-scale animal experiments, the existing method of fixing the tails of miniature animals with rope ligatures is not only time-consuming, but also low in work efficiency.

When using ordinary clips, the contact area between the fixed part and the tail of the miniature animal is small, which can easily cause damage to the tail of the miniature animal

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