Dilation balloon catheter for pathological change of narrow digestive tract
A technology for balloon catheters and digestive tracts, applied in the direction of balloon catheters, catheters, dilators, etc., to achieve the effects of strong practicability, increased tensile and corrosion resistance, and easy bending
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[0053]The preparation steps of the quaternary ammonium salt modified chitosan include:
[0054](1) Dissolve chitosan in organic acid and stir for 2-3 hours at 20-30°C;
[0055](2) Cool the product obtained in step (1) to 0-10°C, then add cyanuric chloride and tetrahydrofuran, and stir and react for 8-10 hours;
[0056](3) The system obtained in step (2) is heated to 20-30°C, quaternary ammonium salt is added, and the reaction is stirred for 6-8 hours;
[0057](4) Carry out solid-liquid separation of the system obtained in step (3), wash the solid with deionized water 3 times, and then vacuum-dry the solid at 70-95°C for 15-20 hours to obtain quaternary ammonium salt modified chitosan;
[0058]The organic acid in step (1) is acetic acid, the mass ratio of cyanuric chloride to chitosan is (1-2.5):1, and the mass ratio of quaternary ammonium salt to chitosan is (1-2): 1.
[0059]The chitosan before modification is commercially available, for example, Shanghai Aladdin Biochemical Technology Co., Ltd., th...
Embodiment 1
[0065]SeeFigure 1-4This embodiment provides a dilatation balloon catheter for narrow digestive tract diseases, including a balloon 1, one end of the balloon 1 is equipped with a soft tip 2, and the other end of the balloon 1 is equipped with a stent for delivery Rod 5, the inside of the balloon 1 is provided with a catheter 3, the outer wall of the catheter 3 is provided with a developing ring 4 at even intervals, a channel is formed between the catheter 3 and the stent delivery rod 5, the channel communicates with the sealed space, and the channel is provided with an inflation port When medical staff use it, under the supervision of the endoscope or other auxiliary equipment, send the balloon 1 through the stent delivery rod 5 and the catheter 3 to the narrow distal end, and confirm that the balloon 1 is fully extended out of the endoscope and is in a proper position. The imaging rings 4 on the outer wall of the catheter 3 are located at both ends of the stenosis. The stenosis can ...
Embodiment 2
[0070]A dilatation balloon catheter for narrow digestive tract disease, the specific implementation is the same as that in Example 1. The difference is that the material of the nylon layer 13 is modified nylon 6.
[0071]The raw materials of the modified nylon 6 include: 60 parts of nylon 6 base material, 7 parts of glycidyl ester, 5 parts of inorganic filler, 7 parts of plasticizer, 1 part of antioxidant, and 3 parts of chitosan.
[0072]The nylon 6 base material was purchased from Dongguan Juntai New Material Technology Co., Ltd.
[0073]The inorganic filler is nano-montmorillonite, purchased from Zhejiang Fenghong New Material Co., Ltd., and the article number is DK4.
[0074]The glycidyl esters are butyl glycidyl and glycidyl neodecanoate, and the weight ratio of butyl glycidyl and glycidyl neodecanoate is 3:1. The CAS number of butyl glycidyl is 2461-40-7, and the CAS number of glycidyl neodecanoate is 26761-45-5.
[0075]The chitosan is (2,3-epoxypropyl)ethyl bis(2-hydroxyethyl)ammonium chlo...
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