Formula with a specific beta-lactoglobulin peptide

Abstract

A formula comprising a whey protein hydrolysate comprising specific beta-lactoglobulin derived peptides and probiotics for inducing oral immune tolerance against milk protein, preventing or treating of oral immune intolerance against milk protein, and / or reducing the risk of developing oral immune intolerance against milk protein.

Description

technical field [0001] The present invention is in the field of formulas comprising hydrolyzed milk protein for infants suffering from or at risk of developing milk protein allergy. Background technique [0002] Dietary protein exposure to the immune system in the gastrointestinal tract. As the immune system's default response, people develop oral tolerance to these harmless food proteins. The development of oral immune tolerance is highly present in infants who are exposed to many harmless proteins early in life through exposure to dietary proteins. Food allergies occur when this natural response to harmless proteins is deviated. It is generally accepted that the prevalence of food allergy has been increasing in recent decades, especially in Western countries. Milk allergy is the leading food allergy in early life and currently affects 2-5% of infants, and a higher percentage are at risk of developing it. [0003] For infants with cow's milk protein allergy, commerciall...

AI Technical Summary

Problems solved by technology

[0014] However, the hypoallergenic compositions of the prior art typically only avoid the presence of potential allergens—thus failing to address the problem—and / or by requiring the presence of specific ingredients such as growth factors or synthetic or purified peptide) to provide its effect

Furthermore, peptides identified in the prior art may not be suitable for inducing oral immune tolerance in large human populations

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