Composition capable of lowering uric acid and preparation method thereof

Abstract

The invention provides a composition capable of lowering uric acid and a preparation method thereof, and relates to the field of health food. The main functional components of the composition includetheaflavin, resveratrol, dihydromyricetin, theanine and cordycepin in set proportion. The composition mainly plays a role to lower the uric acid and resist to gout by inhibiting the activity of xanthine oxidase, adjusting related anionic transporter mRNA and protein expression levels and promoting uric acid excretion; the composition can also relieve the matrix degradation of chondrocyte after IL-1[beta] stimulation and reduce the expression of inflammatory factors, so that the symptoms of osteoarthritis and bone and joint pain can be relieved; and the composition is significant in efficacy, obvious in uric acid lowering, good in safety and convenient in taking, and has good development and application prospects.

Description

technical field [0001] The invention relates to the field of health food, in particular to a composition for reducing uric acid and a preparation method thereof. Background technique [0002] Gout is a disease caused by increased purine biosynthesis, excessive production of uric acid, or poor excretion of uric acid, resulting in elevated blood uric acid and deposition of urate crystals in the synovium, synovial bursa, cartilage and other tissues. Recurrent inflammatory disease, one of the most common types of arthritis in adults. The main goals of clinical drug treatment for gout are to control the acute attack of the disease, correct high uric acid, prevent arthritis recurrence and urate deposition, and protect kidney function. [0003] At present, most of the chemical drugs for lowering uric acid are likely to cause toxic side effects. For example, the drug allopurinol, which inhibits the production of uric acid, has a high incidence of adverse reactions. About 2% of pati...

AI Technical Summary

Problems solved by technology

[0003] At present, most of the chemical drugs for lowering uric acid are likely to cause toxic side effects. For example, the drug allopurinol, which inhibits the production of uric acid, has a high incidence of adverse reactions. About 2% of patients will experience allergic reactions, which may sometimes be serious and fatal. The mortality rate is about 20%; uricase drugs that promote uric acid excretion can easily induce acute gout, and about 4.5% of patients will have hypersensitivity reactions. At the same time, patients often produce antibodies to this type of drug, which reduces the curative effect