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Preparation method of sporoderm-broken ganoderma lucidum spore powder capsules and sporoderm-broken ganoderma lucidum spore powder capsules

A technology for wall-breaking Ganoderma lucidum spore powder and Ganoderma lucidum spore powder, which is applied in the directions of capsule delivery, powder delivery, and pharmaceutical formulations, to achieve the effects of significant active ingredient content, reduced production costs, and easy absorption.

Active Publication Date: 2020-12-01
盈姿生物科技(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Aforesaid related technology, although improved the content of the polysaccharide in the extract to a certain extent, how to improve the effective content of sterol class active substance in making Ganoderma lucidum spore powder capsule then did not involve

Method used

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  • Preparation method of sporoderm-broken ganoderma lucidum spore powder capsules and sporoderm-broken ganoderma lucidum spore powder capsules
  • Preparation method of sporoderm-broken ganoderma lucidum spore powder capsules and sporoderm-broken ganoderma lucidum spore powder capsules
  • Preparation method of sporoderm-broken ganoderma lucidum spore powder capsules and sporoderm-broken ganoderma lucidum spore powder capsules

Examples

Experimental program
Comparison scheme
Effect test

preparation example A

[0050] A kind of preparation technology of broken ganoderma lucidum spore powder, the steps are as follows:

[0051] P1. According to the ratio of adding 75 kg of water to every 3 kg of Ganoderma lucidum spore powder, add water to the Ganoderma lucidum spore powder, stir to make the Ganoderma lucidum spore powder fully dispersed, and then naturally settle for 1.5 hours; after precipitation, remove the upper clear water and keep the bottom sedimentation mixture; Repeat the aforementioned cleaning operation 5 times until there is no suspended matter in the upper clear water, and the spore powder must be cleaned;

[0052] P2. Add the cleaned spore powder to 75㎏ clear water, soak for 1.5h, then fully stir again and filter with a double-layer filter. The filtrate containing Ganoderma lucidum spore powder; standing to allow the filtrate to naturally settle to layers, remove the supernatant, and keep the bottom spore powder mixture;

[0053] P3. For the spore powder mixture obtained...

preparation example B-D

[0056] The preparation examples B-D all involve a preparation process of the broken ganoderma lucidum spore powder, and the process steps are basically the same, and the only difference is that the process parameters are different.

[0057] The process steps are as follows:

[0058] P1. According to the ratio of adding 70-80kg of water per 3kg of Ganoderma lucidum spore powder, add water to the Ganoderma lucidum spore powder, stir to make the Ganoderma lucidum spore powder fully dispersed, and then settle naturally. The precipitation time is 1.0-2.0 hours; after precipitation, remove the upper layer Clean water, keep the sediment mixture at the bottom; repeat the operation 4 to 6 times until there is no suspended matter in the upper clear water, and the spore powder must be cleaned;

[0059] P2. Add the cleaned spore powder to 70-80kg of clean water, soak for 1.0-2.0 hours, then fully stir again and filter, using a double-layer filter to filter, the mesh number of the first fi...

preparation example a

[0068] A preparation process of Ganoderma lucidum fine powder, the process steps are as follows:

[0069] S1. Take Ganoderma lucidum slices, add 22.5kg of water per 1㎏ Ganoderma lucidum slices, add water to soak for 25min, wash with water, drain, and get washed Ganoderma lucidum slices;

[0070] S2. Add the washed ganoderma lucidum slices to 15 kg of water, heat, extract at 100°C for 1.0 hour, filter and retain the filtrate, and concentrate the filtrate, the concentration end point is Baume degree 1.2;

[0071] S3, adding the concentrated filtrate to ethanol with a concentration of 80% in a mass ratio of 1:2.5 for alcohol precipitation, and standing for stratification;

[0072] S4. Remove the alcohol precipitation supernatant in step S3, keep the precipitate, and dry it in vacuum to obtain ganoderma lucidum powder for later use.

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Abstract

The invention relates to the field of health-care medicinal preparations, and particularly discloses a preparation method of sporoderm-broken ganoderma lucidum spore powder capsules and the sporoderm-broken ganoderma lucidum spore powder capsules. The preparation method of the sporoderm-broken ganoderma lucidum spore powder capsules comprises the following steps: uniformly mixing 94-98% of sporoderm-broken ganoderma lucidum spore powder and 2-6% of ganoderma lucidum fine powder in percentage by mass, and performing granulating and freeze-drying to obtain freeze-dried granules of which the water ratio is less than 7%; and filling capsules to obtain the sporoderm-broken ganoderma lucidum spore powder capsules. The sporoderm-broken ganoderma lucidum spore powder is prepared through the procedures of cleaning, soaking, filtering, freeze drying and sporoderm breaking; and the ganoderma lucidum fine powder is prepared through the procedures of soaking, washing, extracting, concentrating, alcohol precipitating and drying. The contents of polysaccharides, spore oil and ergosterol in the sporoderm-broken ganoderma lucidum spore powder capsules prepared by the method are high, and meanwhile,the active ingredients have the advantage of being easily absorbed and utilized by a human body. The invention also correspondingly discloses the sporoderm-broken ganoderma lucidum spore powder capsules which are prepared by the preparation method.

Description

technical field [0001] The invention relates to the field of health-care medicine preparations, more specifically, it relates to a preparation method of a broken-walled ganoderma lucidum spore powder capsule and a broken-walled ganoderma lucidum spore powder capsule. Background technique [0002] As a traditional Chinese herbal medicine, Ganoderma lucidum has been used for more than 2,000 years. Ganoderma lucidum used as a Chinese herbal medicine is mainly the dry fruiting body of Ganoderma lucidum or Ganoderma sinense. Studies have shown that Ganoderma lucidum extract can enhance immunity or directly induce cancer cell death to exert anti-cancer activity. Ganoderma lucidum spores are the seeds released by ejection after the development of Ganoderma lucidum, and they are powdered after being concentrated, commonly known as Ganoderma lucidum spore powder. Ganoderma lucidum spore powder contains high polysaccharides, and polysaccharides are recognized as effective ingredients...

Claims

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Application Information

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IPC IPC(8): A61K36/074A61K9/48A61P35/00A61P37/04A61K9/19
CPCA61K36/074A61K9/4808A61P37/04A61P35/00A61K9/19A61K2236/13A61K2236/331
Inventor 张晓鑫宋鸿飞
Owner 盈姿生物科技(上海)有限公司
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