Microorganism killing composition and preparation method thereof

A composition and microbial technology, applied in the direction of pharmaceutical formulations, medical preparations with no active ingredients, medical preparations containing active ingredients, etc., can solve the problem of long-term or frequent use of exposed skin, inability to provide continuous protection for a long time, easy Cause fire or explosion and other problems, achieve the effect of prolonging the effective sterilization time, preventing dry or chapped hands, and the preparation method is simple and easy to operate

Inactive Publication Date: 2020-11-06
FUAN PHARMA LYBON PHARMA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the prior art, chlorhexidine gluconate and didecyl diammonium chloride are all used in conjunction with ethanol, though there is a good bactericidal effect, there are also obvious defects: 1, due to the strong volatility of ethanol, it cannot Provides continuous protection for a long time
2. There is obvious irritation, which is not conducive to long-term or frequent use of bare skin
3. Ethanol has great potential safety hazards, which can easily cause fire or explosion

Method used

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  • Microorganism killing composition and preparation method thereof
  • Microorganism killing composition and preparation method thereof
  • Microorganism killing composition and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0038] The microbial disinfecting composition of the present embodiment comprises following components and weight percentage thereof:

[0039]

[0040] The guanidine disinfectant used was chlorhexidine gluconate. Chlorhexidine gluconate is added in the form of an aqueous solution of chlorhexidine gluconate. The mass concentration of chlorhexidine gluconate in the chlorhexidine gluconate aqueous solution is 18.2%.

[0041] The cationic surfactant is didecyl ammonium dichloride. Didecyl ammonium dichloride was added in the form of an aqueous solution of didecyl diammonium chloride. The mass concentration of didecyl diammonium chloride in the didecyl diammonium chloride aqueous solution is 80.1%.

[0042] The emollient is propylene glycol.

[0043] The foaming agent is undecylformamidopropyltrimethylammonium sulfate.

[0044] The pH adjuster is lactic acid, and the pH value is 5.15.

[0045] The preparation method of the microbial disinfecting composition of the present ...

Embodiment 2

[0051] The microbial disinfecting composition of the present embodiment comprises following components and weight percentage thereof:

[0052]

[0053] The guanidine disinfectant used was chlorhexidine gluconate. Chlorhexidine gluconate is added in the form of an aqueous solution of chlorhexidine gluconate. The mass concentration of chlorhexidine gluconate in the chlorhexidine gluconate aqueous solution is 18.2%.

[0054] The cationic surfactant is didecyl ammonium dichloride. Didecyl ammonium dichloride was added in the form of an aqueous solution of didecyl diammonium chloride. The mass concentration of didecyl diammonium chloride in the didecyl diammonium chloride aqueous solution is 80.1%.

[0055] The emollient is propylene glycol.

[0056] The foaming agent is undecylformamidopropyltrimethylammonium sulfate.

[0057] The pH regulator is lactic acid, and the pH value is 4.18.

[0058] The preparation method of the microorganism disinfecting composition of the prese...

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PUM

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Abstract

The invention discloses a microorganism killing composition and a preparation method thereof; the composition comprises a guanidine disinfectant and a cationic surfactant, is supplemented by an emollient, a foaming agent, a pH regulator and the like, and does not contain ethanol. The composition provided by the invention not only has a good bactericidal effect on pyogenic coccus, enteropathogenicbacteria, pathogenicity saccharomycetes, common nosocomial infection bacteria and the like, but also has a killing effect on envelope coronavirus.

Description

technical field [0001] The invention belongs to the technical field of microorganism disinfecting, and in particular relates to a microorganism disinfecting composition and a preparation method thereof. Background technique [0002] Currently, there is no definitive and effective treatment or vaccine for the 2019 novel coronavirus. Treatment is mainly support for symptomatic and moderately suppressed immunity. How to effectively block the spread of the virus and establish daily protection awareness is a very effective preventive measure. An antiviral microbial disinfecting composition can effectively block or reduce the risk of contact transmission and is of great significance in protecting people's health. [0003] The disinfectant is mainly a combination of alcohols, disinfectants, surfactants, foaming agents, etc. The more commonly used disinfectants are guanidine disinfectants, which have stable properties, good bactericidal effect and low irritation. In the prior ar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/785A61K31/155A61K31/14A61K47/10A61K47/20A61K47/18A61P31/04A61P31/14A61P31/10A61P31/02
CPCA61K31/14A61K31/155A61K31/785A61K47/10A61K47/183A61K47/20A61P31/02A61P31/04A61P31/10A61P31/14A61K2300/00
Inventor 张涛王立黄耀
Owner FUAN PHARMA LYBON PHARMA TECH
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