Carbocisteine tablet preparation process and equipment

Abstract

The invention discloses a carbocisteine tablet. The carbocisteine tablet is prepared from the following components in parts by weight: 1000 parts of carbocisteine, 120 parts of corn starch, 200 partsof pregelatinized starch, 2800 parts of powdered sugar, 200 parts of low-substituted hydroxypropyl cellulose, 500 parts of 30% ethanol, 16.5 parts of magnesium stearate, 120 parts of carboxymethyl starch sodium, 120 parts of microcrystalline cellulose, 15 parts of steviosin and 3 parts of pineapple essence. Preparation equipment comprises a mixing tank, reciprocating motion mechanisms are installed on the two sides of the mixing tank respectively, a protection box is installed on each reciprocating motion mechanism, a cavity is formed in the protection box, an automatic lifting mechanism is arranged in the cavity, a supporting column is installed on the automatic lifting mechanism, and a transverse plate is fixed to the upper end of the supporting column. According to the invention, not only can the total mixing processing capacity of the carbocisteine tablet be enlarged, but also the mixing effect during total mixing can be ensured, the processing time is greatly shortened, the processing efficiency is enhanced, and the production cost is reduced.

Description

technical field [0001] The invention relates to the technical field of carbocisteine ​​tablet processing, in particular to a preparation process and equipment for carbocisteine ​​tablets. Background technique [0002] Carbocisteine ​​mainly acts on the secretion of bronchial glands, increasing the secretion of low-viscosity salivary mucin and reducing the production of high-viscosity fucoidal mucin, thus reducing the viscosity of sputum and making it easier to cough up. It can be taken orally The effect is quick, because it is widely used in the treatment of chronic bronchitis, bronchial asthma and other diseases. [0003] Existing product yield is on the low side (80.0%) in the existing carbocisteine ​​production technology production at present, the problems such as product content is not high (98.5%), and it has reduced the drug effect of carbocisteine ​​and to a certain extent quality, which affects the therapeutic effect of the drug; and in the production process of ca...

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Problems solved by technology

[0003] Existing product yield is on the low side (80.0%) in the existing carbocisteine ​​production technology production at present, the problems such as product content is not high (98.5%), and it has reduced the drug effect of carbocisteine ​​and to a certain extent quality, which affects the therapeutic effect of the drug; and in the production process of carbocisteine ​​tablets, after the processing of different raw materials, it is necessary to make it carry out the total blending operation, but the total blending operation of the existing carbocisteine ​​tablets The method is to use a simple mixing mixer for stirring and mixing. This method is not only inefficient, but also takes a long time to mix. In addition, its single mixing volume is small, which seriously reduces the processing efficiency of carbocisteine ​​tablets. Therefore, we propose a A kind of carbocisteine ​​sheet preparation technology and equipment solve the above problems

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