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Application of Ferrostatin-1 and derivative thereof in medicine for treating or preventing ionizing radiation damage

A technology of ionizing radiation and derivatives, applied in the field of medicine, can solve the problems of limited drugs, achieve the effects of reducing side effects, significant effects, and easy promotion and use

Inactive Publication Date: 2020-09-04
INST OF RADIATION MEDICINE CHINESE ACADEMY OF MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, currently available drugs for the treatment of ionizing radiation damage are very limited

Method used

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  • Application of Ferrostatin-1 and derivative thereof in medicine for treating or preventing ionizing radiation damage
  • Application of Ferrostatin-1 and derivative thereof in medicine for treating or preventing ionizing radiation damage
  • Application of Ferrostatin-1 and derivative thereof in medicine for treating or preventing ionizing radiation damage

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Embodiment Construction

[0031] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0032] The embodiment of the present invention discloses the application of Ferrostatin-1 and its derivatives in the preparation of medicines for treating or preventing ionizing radiation damage.

[0033] Among them, the drugs include drugs for the prevention / treatment of radiation-induced intestinal injury caused by ionizing radiation.

[0034] Further, the drugs include drugs for the prevention / treatment of radioactive bone marrow injury caused by ionizing r...

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PUM

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Abstract

The invention discloses an application of Ferrostatin-1 and a derivative thereof in a medicine for treating or preventing ionizing radiation damage, and relates to the technical field of medicines. The invention specifically discloses the application of Ferrostatin-1 and the derivative thereof in preparation of the medicine for preventing / treating radioactive intestinal injury, radioactive bone marrow injury and body DNA injury caused by ionizing radiation. The Ferrostatin-1 and the derivative thereof provided by the invention have a protective effect on natural ionizing radiation and artificial radiation, and can be used as the medicine for preventing living body injury caused by radioactive substance radiation, nuclear substance leakage, space ionizing radiation and tumor radiotherapy. The invention provides a new idea for the application of Ferrostatin-1, and provides a new reference for medicines for treating or preventing ionizing radiation damage.

Description

technical field [0001] The invention relates to the technical field of medicine, and more specifically relates to the application of Ferrostatin-1 and its derivatives in the preparation of medicines for treating or preventing ionizing radiation damage. Background technique [0002] Radiation can be divided into non-ionizing radiation and ionizing radiation. Among them, the energy of ionizing radiation is stronger than that of non-ionizing radiation, which can cause greater damage to human health. Ionizing radiation includes natural ionizing radiation and artificial radiation, and natural ionizing radiation includes cosmic rays, earth-native radionuclides, decay products of radon in the air, and various naturally occurring radionuclides; artificial radiation includes medical X-rays, Radioactive dust from nuclear weapons tests, radioactive waste discharged by the nuclear industry, industrial gamma rays, 60Co rays, heavy ion radiation, radiation in tumor radiotherapy, etc. In...

Claims

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Application Information

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IPC IPC(8): A61K31/136A61P17/16
CPCA61K31/24A61P17/16
Inventor 李德冠董辉樊赛军董银萍王梅芳张远洋吴静张俊伶路璐
Owner INST OF RADIATION MEDICINE CHINESE ACADEMY OF MEDICAL SCI
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