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Paste wound dressing for efficient repair of skin superficial injury and preparation method thereof

A technology for wound dressings and superficial injuries, applied in medical science, bandages, etc., can solve the problems of easily leaving scars, affecting the appearance of the skin, and prone to fine scars, so as to reduce the formation of scars and optimize the skin and experience. , Improve the effect of the repair effect

Active Publication Date: 2020-07-24
绽妍生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, fine scars are prone to appear after wound healing, and middle-aged and elderly skin wounds are relatively more likely to leave scars after wound healing, which affects the appearance of the skin

Method used

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  • Paste wound dressing for efficient repair of skin superficial injury and preparation method thereof
  • Paste wound dressing for efficient repair of skin superficial injury and preparation method thereof
  • Paste wound dressing for efficient repair of skin superficial injury and preparation method thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0025] The preparation method of the ointment wound dressing of above-mentioned embodiment 1-3, comprises the following steps:

[0026] (1) Preparation of solution A: add about 20% of the total amount of water into a clean and dry preparation tank, slowly add weighed sodium hyaluronate, sodium alginate, trehalose, and ethyl p-hydroxybenzoate in sequence, Stir for 5-18 minutes, let it stand still, make it fully infiltrate and swell after absorbing water, and obtain solution A;

[0027] (2) Preparation of Solution B: Add weighed white oil, isohexadecane, simethicone and cetostearyl alcohol in sequence in a clean and dry vacuum homogeneous emulsification machine oil phase pot, stir and heat to 65~ 100°C (±5°C), make it dissolve completely to obtain solution B;

[0028] (3) Preparation of solution C: Add the weighed balance of water, butylene glycol, glycerin, pentylene glycol, ceteareth-25 in the main pot of a clean and dry vacuum homogeneous emulsifier, Heat to 65-100°C (±5°C)...

Embodiment 4

[0031] The difference between this embodiment and Example 3 is that every kilogram of ointment wound dressing also contains the raw materials of the following quality: python oil 0.65g and Cortex diffusa extract 0.2g; said python oil is commercially available python oil, which consists of It is obtained by artificially cultivating boa constrictors. The preparation method of the extract of Echinacea diffusa includes the following steps: take Echinacea diffusa, wash it, first use 70v / v% ethanol solution to carry out the first alcohol extraction for 1h, and then extract it at 80v / v% ethanol solution for the second alcohol extraction for 2 hours, combine the extracts, concentrate under reduced pressure, sequentially use 10v / v% ethanol solution, 60v / v% ethanol solution to elute and purify through macroporous adsorption resin, collect the eluate, Concentrate and dry to obtain the extract of Diphtheria diffusa;

[0032] (1) Preparation of solution A: Add about 20% of the total amoun...

Embodiment 5

[0036] Example 5 - the difference between this example and Example 4 is that python oil 0.5g and Dichotoma diffusa extract 0.3g.

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Abstract

The invention provides a paste wound dressing for efficient repair of skin superficial injury and a preparation method thereof. Each kilogram of the paste wound dressing comprises the following raw materials by mass: 65-95g of glycerin, 35-60g of cetostearyl alcohol, 35-60g of butanediol, 85-100g of white oil, 58-84g of isohexadecane, 15-25g of dimethicone, 15-25g of trehalose, 15-25g of pentanediol, 7-16g of ceteareth-25, 0.3-0.8g of sodium alginate, 1-4g of sodium hyaluronate and 0.5-1.2g of ethyl p-hydroxybenzoate. The paste wound dressing provided by the invention creates a good repair environment for superficial injury skin, well inhibits the growth of wound bacteria, promotes the generation of fibroblasts, stimulates angiogenesis, and has a good repair effect on skin superficial injury.

Description

technical field [0001] The invention relates to the technical field of wound dressings, in particular to an ointment wound dressing for efficient repair of superficial skin damage and a preparation method thereof. Background technique [0002] In life and work, many people often have superficial skin injuries, and if they are allowed to heal naturally, it is easy to leave scars. Skin wound dressings form a protective layer on the surface of skin wounds to act as a physical barrier, and are used for the care of superficial wounds such as abrasions and cuts and the surrounding skin. However, fine scars are prone to appear after wound healing, and middle-aged and elderly skin wounds are relatively more likely to leave scars after wound healing, which affects the appearance of the skin. In addition, people pay special attention to the repair of wounds after medical surgery, and have extremely high requirements for the appearance of the repaired skin. Therefore be badly in need...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0019A61L26/0023A61L26/0057A61L26/0066A61L2300/232A61L2300/30A61L2300/404A61L2300/412
Inventor 舒凌
Owner 绽妍生物科技有限公司
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