External efficient acne treatment cosmeceutical formula and preparation method

An anti-acne and formula technology, which is applied in the field of medicine, can solve problems such as the imbalance of normal skin microbial flora, the slow effect of Chinese herbal medicine extracts, and damaged skin barriers, and achieve the effects of preventing rough skin, accelerating wound healing, and inhibiting excess secretion

Pending Publication Date: 2020-06-26
曾宪华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Aiming at the deficiencies of the prior art, the present invention provides an external high-efficiency anti-acne cosmeceutical formula and preparation method, which solves the problem that Chinese herbal medicine extracts are slow to take effect, and keratolytic agents are likely to cause skin dryness and skin barrier damage; although antibiotics are quick to take effect, However, long-term use will produce drug resistance, and it is also very easy to cause the imbalance of the normal microbial flora of the skin, and the problem of repeated acne

Method used

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  • External efficient acne treatment cosmeceutical formula and preparation method
  • External efficient acne treatment cosmeceutical formula and preparation method
  • External efficient acne treatment cosmeceutical formula and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Proportionally prepare the following materials:

[0028]

[0029] Phase A: After the water is heated and boiled, make a paste of propylene glycol and xanthan gum, slowly add it to the boiling hot water, stir until it dissolves evenly, then add glycerin and allantoin in turn, when the water temperature drops to 50°C Add capryloylglycine, matrine, aloe freeze-dried powder, nicotinamide, tocopheryl phosphate, pyridoxine, etc. and stir to dissolve evenly;

[0030] Phase B: Prepare ethanol according to the proportion of the formula, first add the weighed salicylic acid into the ethanol and stir until dissolved, then add menthol, azone, PEG-40 hydrogenated castor oil, etc. and stir well; mix phase A and B Mix the phases together and stir properly, finally add phase C and stir evenly, let it stand overnight until it is clear and transparent, and fill it into a bottle.

Embodiment 2

[0032] Proportionally prepare the following materials:

[0033]

[0034] Phase A: After the water is heated and boiled, make a paste of propylene glycol and xanthan gum, slowly add it to the boiling hot water, stir until it dissolves evenly, then add glycerin and allantoin in turn, when the water temperature drops to 40°C Add capryloylglycine, matrine, aloe freeze-dried powder, nicotinamide, tocopheryl phosphate, pyridoxine, etc. and stir to dissolve evenly;

[0035] Phase B: Prepare ethanol according to the proportion of the formula, first add the weighed salicylic acid into the ethanol and stir until dissolved, then add menthol, azone, PEG-40 hydrogenated castor oil, etc. and stir well; mix phase A and B Mix the phases together and stir properly, finally add phase C and stir evenly, let it stand overnight until it is clear and transparent, and fill it into a bottle.

Embodiment 3

[0037] Proportionally prepare the following materials:

[0038]

[0039] Phase A: After the water is heated and boiled, make a paste of propylene glycol and xanthan gum, slowly add it to the boiling hot water, stir until it dissolves evenly, then add glycerin and allantoin in sequence, and when the water temperature drops to 45 Add capryl glycine, matrine, aloe freeze-dried powder, nicotinamide, tocopheryl phosphate, pyridoxine, etc. and stir to dissolve evenly;

[0040] Phase B: Prepare ethanol according to the proportion of the formula, first add the weighed salicylic acid into the ethanol and stir until dissolved, then add menthol, azone, PEG-40 hydrogenated castor oil, etc. and stir well; mix phase A and B Mix the phases together and stir properly, finally add phase C and stir evenly, let it stand overnight until it is clear and transparent, and fill it into a bottle.

[0041] Clinical use effect observation of the present invention:

[0042] 1) Clinical test: Through...

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Abstract

The invention discloses an external efficient acne treatment cosmeceutical formula and a preparation method and relates to technologies and formulae of external skin medicines of the field of medicines. The external efficient acne treatment cosmeceutical formula comprises a phase A, a phase B and a phase C, wherein the phase A comprises 38-60 parts of a water-phase solvent, 10-12 parts of propylene glycol, 5-8 parts of glycerinum, 2.9-7.8 parts of a water-phase skin conditioning agent and 0.1-0.2 part of a thickening agent; the phase B comprises 20-30 parts of a solvent, 0.6-2.3 parts of a skin conditioning agent, 0.5-1 part of a penetrant and 0.3-0.6 part of a solubilizer; and the phase C comprises 0.5-1 part of an antibacterial preservative. The preparation method comprises the followingsteps: performing weighing; preparing the phase A; preparing the phase B; and performing mixing. The external efficient acne treatment cosmeceutical formula and the preparation method are simple in formula and preparation mode and easy in on-scale production, the formula has certain functions of preventing inflammation and inhibiting propagation of propionibacterium acnes, meanwhile, is capable of improving hydration moisturizing functions of skin, and has the characteristics of being remarkable in comprehsenive effect and short in treatment cycle, and the disease is not liable to reoccur after being healed.

Description

technical field [0001] The invention relates to the technical formula of skin external medicine in the field of medicine, in particular to a formula and preparation method of high-efficiency acne-removing cosmeceuticals for external use. Background technique [0002] Acne, commonly known as "acne", "acne", "acne", and the medical name "acne vulgaris", is a chronic inflammatory skin disease of skin hair follicles and sebaceous glands. Acne mainly occurs in areas with abundant sebaceous glands and exuberant seborrhea such as the face, chest, and back. The severity of the rash manifests in turn as acne, papules, pustules, nodules, cysts and other pathological signs. Although acne does not feel uncomfortable to patients, it hinders the appearance of the skin and often causes a certain psychological burden on patients. If it is not treated properly or treated in time, it will cause acne marks, pits, and even permanent scars on the skin. [0003] The formation process of acne: du...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/67A61K8/49A61K8/44A61K8/368A61K8/34A61P17/10A61Q19/00
CPCA61K8/9794A61K8/678A61K8/675A61K8/673A61K8/4946A61K8/44A61K8/368A61K8/34A61K8/4926A61K8/347A61Q19/00A61P17/10
Inventor 曾宪华
Owner 曾宪华
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