Biological film adhesive force detection device and method

Abstract

The device discloses a biological film adhesive force detection device and method. The device comprises a test vessel and a U-shaped pipe, test liquid is contained in the test vessel, a test film is arranged at the top of the test vessel, a defect area is arranged on the test film, and a biological film to be detected covers the defect area and seals the defect area through adhesive force betweenthe biological film to be detected and the test film; the U-shaped pipe is provided with a vertical section, the upper end of the vertical section is a liquid inlet, the other end of the vertical section is horizontally inserted into the test vessel, and the test vessel, the test film and the biological film to be detected form a sealed cavity filled with test liquid. According to the invention, asimple model is used for simulating the leakage condition of physiological liquid such as cerebrospinal fluid and the like; change of the adhesive force between the biological film to be detected andthe test film, such as the change of the adhesive force between the suture-free dura mater (spinal dura mater) patch and a biological film similar to an autologous meninx, is obtained, so that the magnitude of the adhesive force is quickly calculated, and the method has great significance in clinical application of developing biological film products with compact film layers and non-permeability.

Description

technical field [0001] The invention relates to the technical field of biological material detection, in particular to a biofilm adhesion detection device and detection method. Background technique [0002] There are many different biofilms in various physiological parts of the human body, such as bones, eyeballs and various body organs. When the physiological structure of a certain part of the human body is diseased or damaged, surgical repair is required, and corresponding biofilms are required in this process. The biofilm needs to achieve a predetermined adhesion force in order to ensure normal work in the corresponding part. [0003] For example, the dura (spinal) tissue is a natural barrier to protect the brain and spinal cord tissue. If the dura mater is defective, it will easily lead to leakage of cerebrospinal fluid. At present, there are two kinds of dura (spinal) membrane patches on the market: sutured patch and seam-free patch. For the seam-free dura (spinal) p...

AI Technical Summary

Problems solved by technology

[0007] The technical problem to be solved by the present invention is that there is no feasible method in the detection of existing biofilms, and the detection accuracy cannot be guaranteed.

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