Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method ofprobiotic microcapsules by extruding granulation method and product prepared by method

A technology of extrusion granulation and microencapsulation, applied in the direction of bacteria, lactobacilli, bifidobacteria, etc. used in food preparation, can solve the problems of limited application fields, harsh application conditions, and less retention of probiotics

Pending Publication Date: 2020-05-12
INNER MONGOLIA MENGNIU DAIRY IND (GRP) CO LTD
View PDF6 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the products related to probiotics are generally applied in the field of medicine, such as compressed tablets, capsules, powders, etc., generally need to be stored in low temperature refrigeration, and the storage environment is limited. Therefore, the application field is very limited
[0006] In addition, in the field of dairy products, probiotics are added to the products. The embedding technology usually adopts colloid-embedded probiotics, which are in the form of glue drops, and are directly added to the product. However, due to the influence of the production process, the probiotics in the final product The number of bacteria is kept less, and the application conditions are relatively harsh

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method ofprobiotic microcapsules by extruding granulation method and product prepared by method
  • Preparation method ofprobiotic microcapsules by extruding granulation method and product prepared by method
  • Preparation method ofprobiotic microcapsules by extruding granulation method and product prepared by method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0193] 1. Raw materials (based on 1000g dry microcapsules)

[0194] WPI 750g (concentration 11%);

[0195] Water 6068g;

[0196] Bacillus coagulans powder 250g;

[0197] The curing agent solution is 6818ml, the concentration is 0.5mol / L, wherein: the curing agent is a mixed solution of sodium acetate, glacial acetic acid and Tween-20. Sodium acetate is 137g, glacial acetic acid is 100ml, Tween-20 is 2.9g, water is 6718g.

[0198] 2. Preparation method

[0199] a. Mix whey protein with water and stir at 180rpm / min at 4°C for 16 hours;

[0200] b. heat-treat the whey protein solution at 78°C, 95rpm / min, and 45 minutes;

[0201] c. Cool immediately at 0°C; store at 4°C for 12 hours;

[0202] d. Mix 137g of sodium acetate, 100ml of glacial acetic acid and 6718g of water to make a curing agent solution, adjust the pH to 4.6, add 2.9g of Tween-20, mix well and set aside.

[0203] e. Acute angle extrusion granulation method: nozzle combination 200μm / 400μm, voltage 1600mv, freq...

Embodiment 2

[0223] 1. Raw materials (based on 1000g dry microcapsules)

[0224] WPI (the first layer of wall material) 450g (concentration 11%);

[0225] WPI (second layer wall material) 300g (concentration 11%);

[0226] 6068g of water, including 3641g of water for the first layer of wall material and 2427g of water for the second layer of wall material;

[0227] Bacillus coagulans powder 250g;

[0228] The curing agent solution is 6818ml, the concentration is 0.5mol / L, wherein the curing agent is a mixed solution of sodium acetate, glacial acetic acid and Tween-20. Sodium acetate 137g, glacial acetic acid 100ml, Tween-20 2.9g, water 6718g.

[0229] 2. Preparation method

[0230] a. Mix whey protein with water and stir at 180rpm / min at 4°C for 16 hours;

[0231] b. heat-treat the whey protein solution at 78°C, 95rpm / min, and 45 minutes;

[0232] c. Cool immediately at 0°C; store at 4°C for 12 hours;

[0233] d. Mix 137g of sodium acetate, 100ml of glacial acetic acid and 6718g of ...

Embodiment 3

[0257] 1. Raw materials (based on 1000g dry microcapsules)

[0258] WPI (the first layer of wall material) 300g (concentration 11%);

[0259] Palm oil (second layer of wall material) 200g (concentration 100%);

[0260] WPI (the third wall material) 250g (concentration 11%);

[0261] 4450g of water, including 2427g of water for the first layer of wall material and 2023g of water for the third layer of wall material;

[0262] Bacillus coagulans powder 250g;

[0263] 5000ml of curing agent solution, concentration 0.5mol / L, wherein the curing agent is a mixed solution of sodium acetate, glacial acetic acid and Tween-20. Sodium acetate 101g, glacial acetic acid 74ml, Tween-20 2g, water 4926g.

[0264] 2. Preparation method

[0265] a. Mix whey protein with water and stir at 180rpm / min at 4°C for 16 hours;

[0266] b. heat-treat the whey protein solution at 78°C, 95rpm / min, and 45 minutes;

[0267] c. Cool immediately at 0°C; store at 4°C for 12 hours;

[0268] d. Mix 101g o...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
melting pointaaaaaaaaaa
freezing pointaaaaaaaaaa
melting pointaaaaaaaaaa
Login to View More

Abstract

The invention relates to a preparation method of probiotic microcapsules and the probiotic microcapsules prepared by the method. A method combining extruding granulation with spraying granulation through a fluidized bed is adopted. The preparation method comprises the following steps of: (1) performing coating of first-layer microcapsules; (2) optionally performing coating of second-layer microcapsules; and (3) optionally performing continuous coating for the third time or more times on the microcapsules obtained in the step (2).

Description

[0001] References to related applications [0002] This application claims the priority of Chinese Patent Application No. 201811314763.8 filed on November 6, 2018, and the entire content of the application is incorporated herein as a part of the description. technical field [0003] The invention belongs to the field of food biotechnology. More specifically, the present invention relates to a probiotic microcapsule and a preparation method of the probiotic microcapsule. Background technique [0004] Probiotics, as a kind of living microorganisms that can promote the health of the host, have multiple physiological functions in treatment and health care. However, during actual production, storage, and transportation, probiotics are affected by food components (acids, additives, etc.), ambient temperature, and host digestive system (gastric acid, enzymes, bile salts, etc.), resulting in a significant drop in the number of viable bacteria , the number of viable bacteria that f...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/135A23P10/30A23P10/35
CPCA23L33/135A23P10/30A23P10/35A23V2002/00A23V2400/133A23V2400/145A23V2400/151A23V2400/137A23V2400/147A23V2400/143A23V2400/125A23V2400/181A23V2400/165A23V2400/173A23V2400/113A23V2400/175A23V2400/169A23V2400/513A23V2400/515A23V2400/529A23V2400/517A23V2400/249A23V2400/519A23V2400/533A23V2200/224A23V2200/236A23V2200/3204A23V2250/022A23V2250/54252A23V2300/10A23V2250/18
Inventor 马莉任宪峰张杰俞伟祖石红丽石涵羽张志尧樊梦原郑利君王慧李源李文清白皓雪皇永胜王旭姜利温新华
Owner INNER MONGOLIA MENGNIU DAIRY IND (GRP) CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products