Preparation method of ferrous amino acid chelate and iron supplementing preparation thereof

Abstract

The invention provides a preparation method of a ferrous amino acid chelate and an iron supplementing preparation thereof. The preparation method of the ferrous amino acid chelate comprises the following concrete steps: preparing a mixed material from an iron-containing compound and an amino acid ligand according to a specific ratio; adding a proper amount of water into the mixed material; filtering the material for the first time to obtain a first suspension with a solid particle size of less than 20 [mu]m, and adjusting the pH value of the first suspension; carrying out homogenizing treatment so as to enable the particle sizes of solid matters to reach a nanometer level; after the homogenization treatment, and performing filtering for the second time to obtain a second suspension with asolid particle size of less than 100 nm; and finally, subjecting the second suspension liquid to a chelation reaction at a specific temperature and under a specific pressure. According to the invention, the chelation rate and reaction efficiency of a chelation reaction are greatly improved, reaction time is short, the reaction is complete, and the yield of the ferrous amino acid chelate is high. The ferrous amino acid chelate preparation provided by the invention can cover up unpleasant odor, reduce irritation to gastrointestinal tracts and improve iron supplementing effect.

Description

technical field [0001] The invention belongs to the technical field of iron supplement preparations, in particular to a preparation method of amino acid chelated ferrous iron and an iron supplement preparation. Background technique [0002] Anemia is a symptom and biochemical indicator of human diseases. Anemia can cause hypoxia in body tissues, resulting in the inability of body tissues to produce enough energy to meet the needs of body functions. Iron-deficiency anemia, excessive blood loss and iron nutrition deficiency are all causes important factor in anemia. Iron-deficiency anemia (IDA) is an anemia caused by a lack of iron storage in the human body, which leads to a decrease in the synthesis of hemoglobin. Iron deficiency is the most common nutritional deficiency in all countries in the world, and it is one of the nutritional deficiency diseases with the highest incidence in the world. . About 1 / 3 of the world's 5 billion people are anemic. And IDA or iron malnutri...

AI Technical Summary

Problems solved by technology

At present, there are dozens of types of commonly used iron supplement preparations, but the existing iron supplement preparations have some disadvantages: they have a heavy iron smell, which is not easily accepted by consumers; it is easy to cause gastrointestinal discomfort, and users are very It is difficult to persist in taking for a long time, and the tolerance is poor; some iron supplement preparations will interfere with the metabolism of drugs. Therefore, the present invention proposes a preparation method of amino acid chelated ferrous iron and its iron supplement preparation

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