A portable nuclear magnetic resonance organ elasticity non-invasive quantitative detection method

Abstract

The invention discloses a portable nuclear magnetic resonance organ elasticity non-invasive quantitative detection method, which is characterized in that: the invention adopts a portable nuclear magnetic resonance system, a mechanical vibration excitation device and a console to construct a system framework, and the portable nuclear magnetic resonance system mainly includes an NMR spectrum analyzer , a power amplifier, a preamplifier, a transceiver switching module, a portable magnet module and a probe; when the portable nuclear magnetic resonance system acts on the human body, there is no damage to organs and tissues, no wounds, and realizes safe, accurate, quantitative, and non-invasive organ elasticity detection. The system is streamlined, scientific and reasonable, the equipment is simple and optimized, light in weight, small in size, and easy to carry; one-button operation, no operator dependence, high repeatability; widely applicable to bedside detection and rapid screening; no imaging is required, and the measurement time is short , the motion-sensitive gradient has a certain motion frequency selectivity, the measurement process is not easily affected by motion, and the accuracy is high. Overcome the shortcomings of the existing technology.

Description

technical field [0001] The invention relates to the technical field of nuclear magnetic resonance medical detection, in particular to a portable noninvasive quantitative detection method of nuclear magnetic resonance organ elasticity. Background technique [0002] Elasticity is an important mechanical parameter of biological tissue, which characterizes the difficulty of tissue deformation under the action of mechanical external force. Changes in tissue elasticity are closely related to its physiological and pathological state, and thus normal and pathological tissues can be distinguished. At present, detection methods based on tissue elasticity have been actively applied in tumor diagnosis, grading and rehabilitation evaluation of liver fibrosis. In traditional medicine, doctors qualitatively judge tissue elasticity through palpation, and then diagnose lesions. The diagnostic results have large errors and are greatly affected by the operator's subjective influence. In rece...

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Problems solved by technology

[0003] The purpose of the present invention is to provide a portable nuclear magnetic resonance organ elasticity non-invasive quantitative detection method, which reasonably and effectively solves the problem that the ultrasonic elasticity detection in the prior art is highly dependent on the operator, has a low discrimination rate sensitive to motion, and uses magnetic resonance elasticity. The scanning time of imaging detection is too long, the price is high, the equipment resources are tight, and the problems of bedside detection and rapid screening cannot be applied

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