Chinese medicinal granule for preventing and treating mycoplasma pneumonia of swine, and preparation method thereof

A technology of mycoplasma pneumonia and traditional Chinese medicine granules, which is applied in the field of traditional Chinese veterinary medicine, can solve the problems of high recurrence rate, difficulty in eradicating mycoplasma, unsatisfactory use of vaccines, etc., and achieve the effect of reducing phlegm, not easy to drug resistance, and suitable for industrial production

Inactive Publication Date: 2020-03-24
ZHENGZHOU DOURIN VETERINARY TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the use of vaccines against mycoplasma pneumonia in swine is not ideal, and macrolides (such as erythromycin, tylosin), lincosamides (such as lincomycin) and tetracyclines that affect protein synthesis are usually used clinically Drugs such as tetracycline and doxycycline are used for treatment, but these drugs often only relieve clinical symptoms, are not easy to eradicate mycoplasma, and require continuous administration. Once the drug is stopped, the recurrence rate is high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A kind of granule for preventing and treating swine mycoplasma pneumonia is made by the following steps:

[0029] (1) Weigh each raw material according to the following weight (unit: g): Patrinia 200, Forsythia 200, Anemarrhena 100, Scutellaria baicalensis 100, Juhong 100, Baibu 100, Gardenia 100, Tinglizi 50, Licorice 50 ;

[0030] (2) Decoct Patrinia, Forsythia, Anemarrhena, Scutellaria, Juhong, Baibu, Gardenia, Tinglizi and Licorice twice, add 15 times the weight of water for 1 hour each time, and combine twice for decoction cooking liquid. Concentrate the filtrate under reduced pressure to a relative density of 1.30-1.35 extract, dry the extract in vacuum at 90°C to a dry paste, and crush the dry paste into fine powder for later use. Add excipients (lactose and dextrin, 1:1 ratio) to the dry paste fine powder at a ratio of 1:1, and use 80wt% ethanol as a wetting agent to make a soft material. Pass through a 14-mesh sieve to granulate, dry at 60°C, and classify th...

Embodiment 2

[0032] A kind of granule for preventing and treating swine mycoplasma pneumonia is made by the following steps:

[0033] (1) Weigh each raw material according to the following weight (unit: g): Patrinia 100, Forsythia 100, Anemarrhena 100, Scutellaria baicalensis 100, Juhong 100, Baibu 100, Gardenia 100, Tinglizi 30, Licorice 30 ;

[0034] (2) Decoct Patrinia, Forsythia, Anemarrhena, Scutellaria, Juhong, Baibu, Gardenia, Tinglizi and Licorice twice, add 15 times the weight of water for 1 hour each time, and combine twice for decoction cooking liquid. Concentrate the filtrate under reduced pressure to a relative density of 1.30-1.35 extract, dry the extract in vacuum at 90°C to a dry paste, and crush the dry paste into fine powder for later use. Add excipients (lactose and dextrin, 1:1 ratio) to the dry paste fine powder at a ratio of 1:1, and use 80wt% ethanol as a wetting agent to make a soft material. Pass through a 14-mesh sieve to granulate, dry at 60°C, and classify th...

Embodiment 3

[0036] A kind of granule for preventing and treating swine mycoplasma pneumonia is made by the following steps:

[0037] (1) Weigh each raw material according to the following weight (unit: g): Patrinia 400, Forsythia 400, Anemarrhena 300, Scutellaria baicalensis 300, Juhong 300, Baibu 300, Gardenia 300, Tinglizi 150, Licorice 150 ;

[0038] (2) Decoct Patrinia, Forsythia, Anemarrhena, Scutellaria, Juhong, Baibu, Gardenia, Tinglizi and Licorice twice, add 15 times the weight of water for 1 hour each time, and combine twice for decoction cooking liquid. Concentrate the filtrate under reduced pressure to a relative density of 1.30-1.35 extract, dry the extract in vacuum at 90°C to a dry paste, and crush the dry paste into fine powder for later use. Add excipients (lactose and dextrin, 1:1 ratio) to the dry paste fine powder at a ratio of 1:1, and use 80wt% ethanol as a wetting agent to make a soft material. Pass through a 14-mesh sieve to granulate, dry at 60°C, and classify ...

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Abstract

The invention belongs to the field of Chinese veterinary drugs, and specifically relates to a Chinese medicinal granule for preventing and treating mycoplasma pneumonia of swine and a preparation method thereof. The Chinese medicinal granule comprises the following raw materials (by weight): 1-4 parts of dahurian patrinia herb, 1-4 parts of fructus forsythia, 1-3 parts of rhizoma anemarrhenae, 1-3parts of Scutellaria baicalensis, 1-3 parts of exocarpium citri rubrum, 1-3 parts of the tuber of stemona, 1-3 parts of fructus gardenia, 0.3-1.5 parts of semen lepidii and 0.3-1.5 parts of liquorice. The preparation method comprises the following steps: mixing, decocting, filtering, concentrating, drying to obtain a dry paste, crushing the dry paste, adding a proper amount of auxiliary materials, uniformly mixing, granulating, and drying. The Chinese medicinal granule for preventing and treating mycoplasma pneumonia of swine is mainly used for clearing away heat and toxic materials, supplemented by moistening lung, relieving cough, clearing lung heat and toxic materials and bitter cold, lowering lung qi, protecting lung yin and moistening the lung, is safe and effective, has low toxic and side effect, and has no residue.

Description

technical field [0001] The invention belongs to the field of traditional Chinese veterinary medicine, and in particular relates to a traditional Chinese medicine granule for preventing and treating swine mycoplasma pneumonia and a preparation method thereof. Background technique [0002] Mycoplasma swine pneumonia is a chronic respiratory infectious disease with high morbidity and low mortality caused by Mycoplasma hyopneumoniae. Once the disease occurs in a certain place or a certain pig farm, the symptoms of chronic or recessively infected pigs are not obvious or absent. Symptoms, but it will carry bacteria for a long time, become a source of infection, and then infect more susceptible pigs. The disease develops slowly, has a long course, and some are recessive infections, which can spread in pigs for a long time, both horizontally and vertically. The disease is prone to mixed infection with pathogenic microorganisms such as porcine circovirus, Haemophilus parasuis, Borde...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61K9/16A61P11/00A61P31/04
CPCA61K9/1652A61K36/31A61K36/484A61K36/539A61K36/634A61K36/744A61K36/752A61K36/84A61K36/8964A61K36/904A61K2236/331A61P11/00A61P31/04A61K2300/00
Inventor 李继昌王燕
Owner ZHENGZHOU DOURIN VETERINARY TECH
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