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Method for preparing washing-free polyhexamethylene guanidine hydrochloride disinfectant

A technology of polyhexamethyleneguanidine hydrochloride and disinfectant, which is applied in the field of preparation of no-wash polyhexamethyleneguanidine hydrochloride disinfectant, which can solve environmental hazards, poor killing effect, and types of fungicides It can achieve the effect of easy application, wide disinfection range and long-lasting bactericidal ability

Pending Publication Date: 2020-03-13
JILIN NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

What are the defects of these disinfection ingredients: Aldehyde disinfectants have a better bactericidal effect, but they are more harmful to the environment
However, there are very few types of special fungicides for Brucella, and the killing effect is not good. At present, there is no special killing drug

Method used

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  • Method for preparing washing-free polyhexamethylene guanidine hydrochloride disinfectant

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Disposable polyhexamethylene guanidine hydrochloride disinfectant, the preparation method is,

[0023] Dissolve 3 grams of polyhexamethyleneguanidine hydrochloride in 92 grams of medical deionized water, add 1.5 grams of cocoamide betaine (CAB), 0.8 grams of alkyl glycosides (APG), and adjust the pH of the solution with sodium hydroxide When the value reaches 5.0, add the above-mentioned raw materials into the mixing tank, mix well and then pack.

Embodiment 2

[0025] Wash polyhexamethylene guanidine hydrochloride disinfectant, the preparation method is,

[0026] Dissolve 6 grams of polyhexamethyleneguanidine hydrochloride in 92 grams of medical deionized water, then add 3 grams of cocoamide betaine (CAB) and 1.5 grams of alkyl glycosides (APG), and adjust the pH of the solution with sodium hydroxide When the value reaches 4.5, add the above raw materials into the mixing tank, mix well and then pack.

Embodiment 3

[0028] Wash polyhexamethylene guanidine hydrochloride disinfectant, the preparation method is,

[0029] Dissolve 0.5 g of polyhexamethyleneguanidine hydrochloride in 92 g of medical deionized water, then add 2 g of cocoamide betaine (CAB) and 1.0 g of alkyl glycoside (APG), and adjust the pH of the solution with sodium hydroxide When the value reaches 4.8, add the above raw materials into the mixing tank, mix well and then pack.

[0030] Mix the above-mentioned raw materials evenly and pack them into 25ml spray bottles, which are convenient to carry and use. No need to add any propellant when filling. Reduce operating steps, reduce production costs, and improve sterilization efficiency.

[0031] The disinfectant described in the application belongs to the cationic disinfection type, and cannot be used with anionic emulsifiers, such as sodium stearate, lauric acid soap, etc., to avoid reducing the bactericidal effect.

[0032] Test report on disposable polyhexamethyleneguani...

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PUM

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Abstract

The invention belongs to a preparation method of a washing-free polyhexamethylene guanidine hydrochloride disinfectant. The preparation method is as follows: dissolving 0.5-6 g of polyhexamethylene guanidine hydrochloride in 92 g of medical deionized water, adding 1.5-3 g of coconut oil amide betaine (CAB) and 0.8-1.5 g of alkyl glycoside (APG), adjusting pH value of the solution to 4.5-5.0 by using sodium hydroxide, adding the above raw materials into a stirring tank, uniformly mixing, and sub-packaging. The disinfectant has broad sterilization spectrum, quick effect and long lasting sterilization capacity, is safe, nontoxic and environmentally-friendly, has a strong killing effect on Brucella, Escherichia coli, Staphylococcus aureus, Candida albicans and the like, has good stability, hasa validity period of up to two years, has the advantages of easy smearing, rapid penetration, rapid volatilization, no coloring, easy cleaning and the like, can be used for skin and wound disinfection, hand disinfection, air disinfection, gynecology and urological disinfection, drinking water disinfection, etc., and is a novel and ideal convenient disinfectant.

Description

technical field [0001] The invention belongs to the field of disinfectants, in particular to a preparation method of a wash-free polyhexamethyleneguanidine hydrochloride disinfectant. Background technique [0002] In public places where people are relatively concentrated and crowded, such as hospitals, airports, stations, restaurants, offices, etc., it is very easy to cause the spread of bacteria and viruses, resulting in cross-infection of the public. Hospitals, in particular, are not only places where diseases are treated, but also places where diseases may spread. During the transmission of these bacteria and viruses, especially due to the touch of the public's hands, such as the doctor's palpation of the patient, railings, door handles, handrails in the car, etc., is an important factor causing public cross-infection. Combined with the enlightenment given by the epidemic of SARS, we realize the importance of large-scale disease prevention in public places. In this case...

Claims

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Application Information

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IPC IPC(8): A61K8/04A61K8/44A61K8/60A61K8/84A61Q17/00A61Q19/00A61Q19/10
CPCA61K8/84A61K8/44A61K8/604A61K8/046A61Q19/10A61Q17/005A61Q19/00A61K2800/592
Inventor 刘宏李传碧
Owner JILIN NORMAL UNIV
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