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Immunomodulating composition for sports people as well as preparation method and application of composition

A technology for immune regulation and sports people, applied in the directions of bacteria, application, food science, etc. used in food preparation, it can solve the problems of reducing immunity and increasing the sensitivity of upper respiratory tract disorders, so as to enhance immunity, improve exercise status, Simple preparation method

Pending Publication Date: 2020-03-10
GUANGZHOU PROFORCARE PHARMA INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Reduced immunity during the window period, combined with naturally occurring hyperventilation during exercise, leads to increased sensitivity to upper airway disturbances in active individuals

Method used

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  • Immunomodulating composition for sports people as well as preparation method and application of composition
  • Immunomodulating composition for sports people as well as preparation method and application of composition
  • Immunomodulating composition for sports people as well as preparation method and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] The components of the immunoregulatory probiotic composition of the present invention, in parts by weight, are as shown in Table 1:

[0050] The composition ratio of each group in table 1

[0051]

[0052]

[0053] Wherein said Lactobacillus acidophilus DDS-1 contains 1.5×10 live bacteria 10 -4.5×10 11 CFU / g.

[0054] Weigh each material according to the formula ratio, dry at 60°C until the moisture content is lower than 3%, pass through a 60-mesh sieve, and mix evenly. It is prepared into solid beverage, chewable tablet or buccal tablet according to the conventional process in the industry.

Embodiment 2

[0055] Example 2 Effect of probiotic composition on exercise tolerance of mice

[0056] 140 male mice were selected for the experiment, weighing 18-24g, randomly divided into 7 groups, divided into 1 control group and 6 experimental groups, 20 in each group, and each group of mice performed 45min swimming training every day, and the training period was 2 weeks , after the daily training of the mice, they were fed with 20 mL of sports drink prepared by the experimental group 1-3 and the control group 1-3 of the present invention respectively, and the blank group was fed with the basic feed. 30 minutes after the last swimming training, swim to exhaustion, and test the exhaustion swimming time. The experimental results are shown in Table 2 below:

[0057] Table 2 Results of exhaustive swimming time of mice in each group

[0058] group n Exhaustion time (min) exhaustion delay rate blank group 20 240.24±22.75 -- Experimental group 1 20 325.06±30.46 3...

Embodiment 3

[0061] Example 3 Effect of sports health food on ConA-induced lymphocyte transformation response in mice

[0062] 70 Kunming female mice of SPF grade were selected for the experiment, weighing 10-24g, and randomly divided into 7 groups, including 1 control group and 6 experimental groups, 10 mice in each group. Each day, the experimental group 1-2 and the control group 1-2 were fed with 20 mL of sports drink prepared by the experiment group 1-2 and the control group 1-2 respectively, and the blank group was fed with aseptic pure water for four consecutive weeks. ConA induced lymphocyte proliferation experiment.

[0063] Lymphocyte proliferation reaction: add the cell suspension into two wells of a 24-well culture plate, 1 mL per well, 75 μL ConA solution (equivalent to 7.5 μg / mL) in one well, and the other well as a control, in 5% CO 2 , 37 ° C for 72h. 4 hours before the end of the culture, aspirate 0.7 mL of the supernatant from each well, add 0.7 mL of serum-free RPMI 164...

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PUM

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Abstract

The invention provides an immunomodulating composition for sports people. The composition includes the following components in parts by weight: lactobacillus acidophilus, whey protein hydrolysates, whey protein, glucose, medium chain triglyceride, calcium hydrogen phosphate, fructooligosaccharide, yeast powder, edible salt, cocoa powder and yeast beta-glucan, wherein the lactobacillus acidophiluscontains a live bacteria number of 0.15x10<11> to 4.5x10<11> CFU / g. Food prepared from the above composition has a good taste and easily-absorbed nutrients, and significantly improves the immunity andsports endurance of the sports people; and a preparation method of the composition is simple, easy to operate, and suitable for industrial production.

Description

technical field [0001] The invention relates to the field of functional food, in particular to an immune regulation composition for sports people and its application. Background technique [0002] The relationship between physical exercise intensity and immune response is a "J"-shaped curve. [0003] This phenomenon forms a "window period" of up to 72 hours. Reduced immunity during the window period, combined with naturally occurring hyperventilation during exercise, lead to increased susceptibility to upper airway disturbances in active individuals. Mechanical damage to the airways caused by hyperventilation can cause inflammation, asthma-like symptoms, runny nose, fatigue, and fever, which account for 30 to 40% of athletes with upper respiratory tract infections. Upper respiratory infections are a common reason athletes miss training and even competition, and can also affect performance. [0004] Light to moderate-intensity exercise is protective for the gut; vigorous e...

Claims

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Application Information

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IPC IPC(8): A23L33/135A23L33/19A23L33/125A23L33/115A23L33/16A23L33/14A23L33/10A23L2/39
CPCA23L33/135A23L33/19A23L33/125A23L33/115A23L33/16A23L33/14A23L33/10A23L2/39A23V2002/00A23V2400/113A23V2200/3204A23V2200/324A23V2200/314A23V2200/30A23V2250/1944A23V2250/28A23V2250/54252A23V2250/61A23V2250/76
Inventor 吴嘉棋王从峰陈靓朱雪梅徐敏雷雨娴陈惠欣
Owner GUANGZHOU PROFORCARE PHARMA INC
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