Multi-index-based evaluating-optimizing glabrous sarcandra herb preparation technology

Abstract

The invention discloses a multi-index-based evaluating-optimizing glabrous sarcandra herb preparation technology. The multi-index-based evaluating-optimizing glabrous sarcandra herb preparation technology comprises the following steps of HPLC determination of specified components, process optimization of glabrous sarcandra herb leaves, single factor experimental investigation of glabrous sarcandraherb stems, cutting-preparing design scheme of the glabrous sarcandra herb stems, establishment of an AHP model, a comprehensive scoring method and CCD-RSM optimized glabrous sarcandra herb stem cutting-preparing process and verification test. Through a single-factor test, the comprehensive scores of the content of neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid, caffeic acid, isofraxidin, astilbin and rosmarinic acid are taken as the evaluation indicators, a central composite design-response surface methodology is used to screen glabrous sarcandra herb softening and cutting-preparing processes, the glabrous sarcandra herb stems and leaves subjected to process optimization by choosing different treatment methods, a multi-index analytic hierarchy process (AHP) is combined with the central composite design-response surface methodology to optimize the glabrous sarcandra herb preparation technology, the study is beneficial to the further development of glabrous sarcandra herb, and an experimental basis is expected to be provided for the establishment of related preparation specifications and quality standards of glabrous sarcandra herb.

Description

technical field [0001] The invention relates to the technical field of coral coral processing, in particular to a process for processing coral coral based on multi-index evaluation and optimization. Background technique [0002] Grass coral, also known as swollen joint wind, is the dried whole herb of the Chrysanthemum orchidaceae. Pharmacological studies have shown that Coral Cortex has anti-bacterial, anti-inflammatory, hepatoprotective, anti-tumor and other pharmacological effects. Its main active ingredients are flavonoids, phenylpropanoids, coumarins, etc. The processing method of Coral Cortex under the 2015 edition of the Chinese Pharmacopoeia is as follows: "Remove impurities, wash, moisten, cut, and dry". There is no specific standard for processing parameters, and the quality of decoction pieces is difficult to control. If the cutting process of traditional Chinese medicine is only evaluated by the content of a single chemical index component, then The comprehensiv...

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Problems solved by technology

[0003] Aiming at the deficiencies of the prior art, the present invention provides a process based on multi-indicator evaluation to optimize the processing of coral coral, which solves the problem that the processing method of coral coral decoction pieces under the 2015 edition of the Chinese Pharmacopoeia proposed in the background technology is "remove impurities, wash Clean, moisten, cut, and dry", there is no specific processing parameter standard, and the quality of decoction pieces is difficult to control. If the cutting process of traditional Chinese medicine is only evaluated by the content of a single chemical index component to evaluate the pros and cons of the process, multi-components will be ignored. The problem of combined utility between

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