Multimode 3D fluorescence tomography animal molecular imaging scanning equipment

Abstract

The invention discloses multimode 3D fluorescence tomography animal molecular imaging scanning equipment, and belongs to the technical field of optical molecular imaging. The multimode 3D fluorescencetomography animal molecular imaging scanning equipment comprises a light sheltering camera bellows, a sample platform mounted in the light sheltering camera bellows and a computer terminal for controlling the equipment and imaging, wherein the sample platform comprises a transparent platform which is supported by a supporting column; the outer wall of the transparent platform is rotatably connected with a rotating platform through a bearing; the rotating platform is driven by a driving mechanism to rotate; a sample box is placed on the surface of the transparent platform; a CT scanning moduleis placed on the surface of the rotating platform; a CCD camera and an LED array are arranged on the inner wall of the top end of the light sheltering camera bellows; a lens collimator is arranged right below the sample platform, and is connected with a laser through an optical fiber wire; and an FMT scanning module consists of the CCD camera, the lens collimator and the laser. According to the multimode 3D fluorescence tomography animal molecular imaging scanning equipment disclosed by the invention, the CT scanning module is combined with the FMT scanning module, so that dualmode imaging isperformed on live small animals, so that the imaging is enriched.

Description

technical field [0001] The invention relates to the technical field of optical molecular imaging, in particular to a multi-mode 3D fluorescent tomographic animal molecular imaging scanning device. Background technique [0002] In vivo bioluminescence imaging is a molecular and gene expression analysis and detection system developed in recent years. It consists of a sensitive CCD and its analysis software, as well as reporter luciferase (luciferase) and luciferin (luciferin). Using sensitive detection methods, researchers can directly monitor biological processes such as the growth and metastasis of tumors, the development of infectious diseases, and the expression of specific genes in living organisms. Small animal in vivo fluorescence imaging technology has gained more and more attention at home and abroad. Widely used, more and more researchers hope to use this technology to track and observe the growth of tumor cells in living animals and the response to drug treatment f...

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to propose a multi-mode 3D fluorescent tomographic animal molecular image scan in order to solve the problems of poor imaging quality of small animals in the single mode of the above-mentioned active fluorescence imaging equipment, insufficient abundance and inaccurate imaging of small animals when using the FMT scanning mode The equipment has the advantages of combining two modes of CT scanning and FMT scanning, rich and accurate imaging, multiple fluorescent labels, and adjusting the spectrum to make the details of small animal imaging more accurate

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