Multi-joint detection kit for rapidly detecting liver diseases and preparation method thereof

Abstract

The invention discloses a multi-joint detection kit for rapidly detecting liver diseases and a preparation method thereof. The multi-joint detection kit adopts a fluorescence immunochromatographic method; four fluorescence detection cards are prepared from four markers, including angiopoietin-like protein 2 (angptl2), alpha fetoprotein (AFP), serum osteopontin (OPN) and human cartilage glycoprotein (YKL-40), which are used for detecting liver diseases; the four detection cards are arranged and connected together in parallel to form a kit body; every two adjacent detection cards have a sample adding hole; and each detection card is provided with a card reading window. The multi-joint detection kit can detect four different markers of liver diseases at the same time, can comprehensively monitor liver cirrhosis, liver cancer and liver cancer prognosis, and enables early detection of liver diseases to be faster and more precise; and the operation is simple, the detection time is short, four detection results can be obtained only by adding samples twice, and the results can be obtained within 10 minutes after sample adding is completed, so that the multi-joint detection kit is more suitable for primary level application.

Description

technical field [0001] The invention relates to the technical field of disease detection, in particular to a multiple detection kit for rapid detection of liver disease and a preparation method thereof. Background technique [0002] At present, there are more than 2 billion liver disease virus-infected people in the world, and 350 million liver disease virus carriers. Among them, there are 130 million liver disease virus carriers in my country, and 30 million chronic hepatitis B patients. Among Chinese people, 1 in 1 is a carrier of liver disease virus. There are 500,000 new liver disease cases in China every year, and about 280,000 people die from liver disease-related diseases every year, and about 350,000 people die from liver cirrhosis and liver cancer caused by various liver diseases. It can be seen from this that liver disease has become one of the diseases that seriously endanger our physical and mental health. Liver disease can easily develop into liver cancer in th...

AI Technical Summary

Problems solved by technology

Serological testing mainly checks the tumor markers in the serum. At present, the main marker detected is alpha-fetoprotein (AFP), but the sensitivity of alpha-fetoprotein (AFP) in small liver cancer is only about 40%. Only one tumor marker can accurately diagnose the occurrence and development of tumors, and the combined detection of multiple markers can improve the accuracy of detection and avoid missed diagnosis and false positives

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