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Non-formaldehyde environment-friendly pathological tissue fixing agent

A tissue fixation and environmental protection technology, applied in the preservation of plants, the preservation of human or animal bodies, and botanical equipment and methods, can solve the problems of poor pathological tissue softness, poor tissue fixation effect, and volatilization of active ingredients. To achieve the effect of excellent sterilization and anti-mildew function, transparent solution and excellent permeability

Inactive Publication Date: 2019-12-24
宁波化奇工程技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In view of the above-mentioned defects of the prior art, the technical problem to be solved by the present invention is to provide a non-formaldehyde environmental-friendly pathological tissue fixative to completely replace formalin solution, while overcoming the pungent smell of traditional fixatives, volatilization of active ingredients, The preserved pathological tissue has problems such as poor softness and poor tissue fixation effect. At the same time, it creates a good working environment for medical workers and provides high-quality medical pathological tissue. It is bound to promote better medical education and scientific research. faster development

Method used

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  • Non-formaldehyde environment-friendly pathological tissue fixing agent
  • Non-formaldehyde environment-friendly pathological tissue fixing agent
  • Non-formaldehyde environment-friendly pathological tissue fixing agent

Examples

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Effect test

Embodiment 1

[0025] Dissolve 1 kg of vegetable tannins with a tannin content ≥ 8% in 50 kg of a buffer solution with a pH of 4.0, wherein the buffer solution is 374 g of sodium hydroxide, 945 g of citric acid, 50 g of urea, and 203 ml of phosphoric acid. It was prepared by dissolving and diluting 50 kg in ionized water, and finally obtained 50 kg of an environment-friendly pathological tissue fixative with a pH of 4.0.

Embodiment 2

[0027] Dissolve 2 kg of vegetable tannins with a tannin content ≥ 8% in 50 kg of a buffer solution with a pH of 4.5, wherein the buffer solution is 296 grams of sodium hydroxide, 865 grams of citric acid, 45 grams of urea, and 195 milliliters of phosphoric acid. It was prepared by dissolving and diluting 50 kg in ionized water, and finally obtained 50 kg of an environment-friendly pathological tissue fixative with a pH of 4.5.

Embodiment 3

[0029] Dissolve 5 kg of vegetable tannins with a tannin content ≥ 8% in 200 kg of a buffer solution with a pH of 5.0, wherein the buffer solution is 595 grams of sodium hydroxide, 1730 grams of citric acid, 90 grams of urea, and 350 milliliters of phosphoric acid. It was prepared by dissolving and diluting 200 kg in ionized water, and finally obtained 200 kg of environment-friendly pathological tissue fixative with a pH of 4.5.

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Abstract

The invention discloses a non-formaldehyde environment-friendly pathological tissue fixing agent. The invention relates to the technical field of pathological tissue fixation. The pathological tissuefixing agent includes: vegetable tannin and a buffer solution, wherein the content of tannin in the vegetable tannin is more than 8%; the buffer solution is a weakly acidic solution and is a mixed solution of sodium hydroxide, citric acid, urea, phosphoric acid and deionized water; wherein the mass fraction of the vegetable tannin is 2%-10%, the mass fraction of the sodium hydroxide is 0.5%-1%, the mass fraction of the citric acid is 0.865%-3.5%, the mass fraction of the urea is 0.045%-0.2%, the volume fraction of the phosphoric acid is 0.2%-0.48%, and the balance is the deionized water. The pathological tissue fixing agent can completely replace a formalin solution, and meanwhile the problems that a traditional fixing agent is pungent in smell, effective components volatilize, the softness of preserved pathological tissue is poor, and the tissue fixing effect is poor are solved.

Description

technical field [0001] The invention relates to the technical field of pathological tissue fixation, in particular to a formaldehyde-free and environment-friendly pathological tissue fixative. Background technique [0002] Formalin is the most widely used as a corpse preservative. Formaldehyde and benzene have been identified as carcinogens by the World Health Organization. Skin, respiratory mucosa, etc., will eventually lead to abnormal immune function, liver damage and nervous central system, which will lead to fetal malformation, leukemia, chronic respiratory diseases, nasopharyngeal cancer, female menstrual disorders, acute mental depression and other diseases. In addition, specimens stored in formaldehyde solution for a long time will harden, yellow, and have white precipitates and turbidity. The concentration of formaldehyde solution will also decrease due to the volatilization of formaldehyde, and gradually lose the function of preserving specimens. [0003] People a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N1/00A01N3/00
CPCA01N1/00A01N3/00
Inventor 严洁峰冯怡林荣史楷岐
Owner 宁波化奇工程技术有限公司
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