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Mouthwash capable of effectively inhibiting bacteria and preparation method

A mouthwash and matrix technology, applied in the field of oral hygiene care, can solve the problems of treating the symptoms but not the root cause, and the biofilm has no therapeutic effect.

Pending Publication Date: 2019-12-03
伟日(山东)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, other oral products on the market are only oral products that work on the bacteria in the oral cavity, but have no effective therapeutic effect on the biofilm formed by dental plaque, causing the bacteria to continue to attach to the biofilm on the tooth surface after reviving , resulting in a symptom that does not cure the root cause

Method used

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  • Mouthwash capable of effectively inhibiting bacteria and preparation method
  • Mouthwash capable of effectively inhibiting bacteria and preparation method
  • Mouthwash capable of effectively inhibiting bacteria and preparation method

Examples

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Effect test

example 1

[0016] An effective antibacterial mouthwash consisting of antibacterial bio-extract, sodium bicarbonate, biorefined glycerin, peppermint oil, sodium lauryl sulfate, cooling agent WS-23, anticaking agent, sweetener and gargle Saliva base composition, anticaking agent is calcium carbonate, antibacterial biological extract is natamycin, nisin and phenyllactic acid, sweetener is maltooligosaccharide glucose and soybean oligosaccharide, mouthwash base is sodium lactate and purified water, the mass ratio of each component to the total mass is 0.03% of natamycin, 0.03% of nisin, 0.02% of phenyllactic acid, 0.08% of sodium bicarbonate, 0.05% of biorefined glycerin, and 0.05% of peppermint oil , sodium lauryl sulfate 0.03%, maltooligosaccharide glucose 0.05%, soybean oligosaccharide 0.05%, cooling agent WS-23 0.05%, calcium carbonate 0.01%, sodium lactate 0.02%, and the balance is purified water.

[0017] The preparation method of the above-mentioned effective bacteriostatic mouthwash ...

example 2

[0019] An effective antibacterial mouthwash consisting of antibacterial bio-extract, sodium bicarbonate, biorefined glycerin, peppermint oil, sodium lauryl sulfate, cooling agent WS-23, anticaking agent, sweetener and gargle Saliva base composition, anticaking agent is calcium carbonate, antibacterial biological extract is natamycin, nisin and phenyllactic acid, sweetener is soybean oligosaccharide and xylooligosaccharide, mouthwash base is hydrogen phosphate Disodium and purified water, the mass ratio of each component to the total mass is 0.2% natamycin, 0.3% nisin, 0.2% phenyllactic acid, 0.1% sodium bicarbonate, 0.09% biorefined glycerin, peppermint oil 0.09%, sodium lauryl sulfate 0.09%, soybean oligosaccharide 0.07%, xylooligosaccharide 0.05%, cooling agent WS-23 0.1%, calcium carbonate 0.05%, disodium hydrogen phosphate 0.06%, the balance is pure water.

[0020] The preparation method of the above-mentioned effective bacteriostatic mouthwash is to weigh natamycin, nisi...

example 3

[0022] An effective antibacterial mouthwash consisting of antibacterial bio-extract, sodium bicarbonate, biorefined glycerin, peppermint oil, sodium lauryl sulfate, cooling agent WS-23, anticaking agent, sweetener and gargle Composition of saliva base, anticaking agent is potassium ferrocyanide, antibacterial biological extract is natamycin, nisin and phenyllactic acid, sweetener is fructooligosaccharide and isomaltooligosaccharide, mouthwash The matrix is ​​sodium lactate and purified water, and the mass ratio of each component to the total mass is 0.5% natamycin, 0.8% nisin, 0.5% phenyllactic acid, 0.2% sodium bicarbonate, 0.2% biorefined glycerin, mint Oil 0.013%, sodium lauryl sulfate 0.15%, fructooligosaccharide 0.15%, isomaltooligosaccharide 0.09%, cooling agent WS-23 0.2%, potassium ferrocyanide 0.1%, sodium lactate 0.2%, balance for pure water.

[0023] The preparation method of the above-mentioned effective bacteriostatic mouthwash is to weigh natamycin, nisin, and p...

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Abstract

The invention discloses mouthwash capable of effectively inhibiting bacteria and a preparation method thereof. The mouthwash is composed of an antibacterial biological extract, sodium bicarbonate, biologically refined glycerin, peppermint oil, lauryl sodium sulfate, a freshener WS-23, an anti-caking agent, a sweetening agent and a mouthwash matrix. Wherein the antibacterial biological extract is natamycin, nisin and phenyllactic acid; natamycin, nisin and phenyllactic acid are weighed, natamycin, nisin and phenyllactic acid are added into purified water, stirring is carried out through a reaction kettle until natamycin, nisin and phenyllactic acid are dissolved, and other components can be added, stirring at a high speed is carried out until all substances are dissolved, and finally packaging is carried out after sterile filling. The mouthwash disclosed by the invention contains natamycin, nisin and phenyllactic acid, the mouthwash can effectively kill and inhibit G<+> and G<->bacteriasuch as porphyromonas gingivalis, actinobacillus actinomycetemcomitan, Fusobacterium, streptococcus mutans and the like in the oral cavity, has a decomposition effect on plaque biofilms generated byflora, can decompose dental plaque while protecting beneficial bacteria, and has the tooth cleaning effect while sterilizing and removing the plaque.

Description

technical field [0001] The invention relates to the technical field of oral hygiene care, in particular to an effective antibacterial mouthwash and a preparation method. Background technique [0002] Plaque, also known as dental plaque biofilm, refers to the adhesion on the surface of teeth, other oral soft tissues or restorations. It is composed of a large number of intercellular substances such as proteins, polysaccharides, teichoic acid, a small amount of white blood cells, exfoliated Composed of epithelial cells and food residues, a layer of biofilm is formed on the tooth surface. Bacteria in the oral cavity adhere to the film one after another. The bacteria connect and proliferate through adhesion and copolymerization to form a complex flora. It is a non-mineralized According to the different types of bacteria in the plaque and the different adsorption sites, dental plaque can be divided into supragingival plaque and subgingival plaque, smooth surface caries and supragi...

Claims

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Application Information

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IPC IPC(8): A61K8/92A61K8/19A61K8/365A61K8/46A61K8/60A61K8/64A61P1/02A61P31/02A61P31/04A61P31/10A61Q11/00
CPCA61K8/64A61K8/602A61K8/19A61K8/922A61K8/463A61K8/365A61Q11/00A61P1/02A61P31/02A61P31/04A61P31/10
Inventor 许宸华陈卫良李波
Owner 伟日(山东)生物科技有限公司
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