Hydrogel dressing for repairing soft tissue wounds and scars and preparation method thereof

Abstract

The invention belongs to the technical field of medicines, and discloses a hydrogel dressing for repairing soft tissue wounds and scars and a preparation method thereof. The dressing is made of the following components in percentage by weight: 0.0001-0.02% of epidermal growth factor, 0.0001-2% of nano silver, 0.5-5% of lavender essential oil, 0.5-5% of aloe extract, 0.5-5% of pseudo-ginseng extract, 1-5% of skin penetrant, 0.5-5% of penetration enhancer, 6-15% of partially neutralized sodium polyacrylate, 0.5-3% of cross-linking agent, 0.5-3% of cross-linking regulator, 2-5% of filler, 25.0-35.0% of humectant, 3-8% of tackifier and 4-59% of deionized water. The preparation method of the dressing includes the following steps: preparing phase I, preparing phase II, mixing the phase I and thephase II, and preparing a gel patch. The dressing of the invention promotes healing and growth of the wounds, has good breathability, convenience of use, inhibition of wound infection and a wide range of applications.

Description

technical field [0001] The invention relates to the technical field of medicine, more specifically, to a hydrogel dressing for soft tissue wound scar repair and a preparation method thereof. Background technique [0002] Skin and soft tissue protect internal tissues from external damage; carry out metabolism such as absorption, perspiration, secretion of sebum and excretion of waste; and have immune function. It is inevitable that people will suffer from traumas of different severity in their life, especially trauma, natural disasters and surgical trauma after illness are often unavoidable. When the skin damage reaches a certain level, due to the fibroproliferative reaction, the skin wound repair will end in scar formation. All kinds of scars on the body surface will destroy the original skin integrity, damage the appearance, and bring physical and mental harm to the patient. How to repair wounds and remove scars has always been one of the important research topics in the ...

AI Technical Summary

Problems solved by technology

Traditional dressings can keep the wound dry, but cannot effectively prevent the wound from being infected, and are prone to adhesion to the planed surface, which may lead to re-damage of the wound when removed; the new synthetic dressing has good elasticity and air permeability, However, poor hygroscopicity may lead to the formation of fluid accumulation on the wound surface and cause the reproduction of bacteria

Tissue engineering products used in clinical practice have a certain rejection immune reaction, and the treatment effect is not good

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