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Abdominal wall repair patch having elastic enhanced type reticular structure and preparation method of elastic enhanced type abdominal wall repair patch

A mesh structure, enhanced technology, applied in the field of biological 3D printing and prosthetic medicine, can solve problems such as insufficient mechanical properties, and achieve the effects of reducing huge tension, reducing hernia recurrence, and improving elastic properties

Inactive Publication Date: 2019-11-19
SHANGHAI UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to address the deficiencies of the prior art, to provide a novel mesh-structured abdominal wall repair patch and its preparation method, to enhance the elastic performance of the abdominal wall repair patch made of biological materials, and to solve its mechanical properties in the process of repairing the defective abdominal wall. Insufficient problem

Method used

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  • Abdominal wall repair patch having elastic enhanced type reticular structure and preparation method of elastic enhanced type abdominal wall repair patch
  • Abdominal wall repair patch having elastic enhanced type reticular structure and preparation method of elastic enhanced type abdominal wall repair patch
  • Abdominal wall repair patch having elastic enhanced type reticular structure and preparation method of elastic enhanced type abdominal wall repair patch

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Experimental program
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Embodiment 1

[0031] Embodiment one: see Figure 1 ~ Figure 4

[0032] The elastic-enhanced mesh structure abdominal wall repair patch is composed of two layers of patch layers superimposed in parallel, and is characterized in that: the two layers of patch layers have the same mesh structure, the shape of the unit grid is rhombus, and the size and same shape.

Embodiment 2

[0033] Embodiment 2: This embodiment is basically the same as Embodiment 1, and the special features are as follows:

[0034] The two patch layers are prepared by electrohydrodynamic jet printing technology, the first patch layer is printed along the negative direction of the x-axis as a whole, and the second patch layer is printed and formed along the negative direction of the y-axis as a whole, that is, the two The overall printing and forming directions of the layer patch layers are perpendicular to each other. The shape and size of the abdominal wall defect area are obtained by computerized tomography or magnetic resonance imaging, and then the overall size of the abdominal wall repair patch and the shape and size of the diamond-shaped unit grid are obtained through calculation.

Embodiment 3

[0036] The elasticity-enhanced mesh structure abdominal wall repair patch and its preparation method are characterized in that the preparation steps are:

[0037] Step 1. Obtain the shape and size of the abdominal wall defect area through computed tomography or magnetic resonance imaging, and determine the initial length x of the abdominal wall repair patch in the x-axis direction 0 = 30mm and the initial length y in the y-axis direction 0 = 30mm;

[0038] Step 2. Determine the elasticity requirements of the defected abdominal wall region in the x-axis direction and y-axis direction and

[0039] Step 3. According to the elastic demand formula in the x-axis direction Determine the maximum elastic elongation x of the abdominal wall repair patch in the direction of the x-axis 1 =6.21mm, according to the elastic demand formula in the y-axis direction Determine the maximum elastic elongation y of the abdominal wall repair patch in the y-axis direction 1 =6.21mm;

[0040...

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Abstract

The invention relates to an abdominal wall repair patch having an elastic enhanced type reticular structure and a preparation method of the elastic enhanced type abdominal wall repair patch. The patchis characterized in that the patch is prepared by overlapping two patch layers which have identical shapes and sizes and are positioned in the perpendicular printing formation directions in parallel, and the problem that the mechanical performance of the abdominal wall repair patch made of biological materials in repairing of abdominal-wall defect is poor is solved. The abdominal wall repair patch having the elastic enhanced type reticular structure disclosed by the invention has the characteristics that the improved elastic enhanced type reticular structure changes the own shape more easilyalong with the change of force and resists tension caused by abdominal exercises, so that the patch has higher elastic performance and reduces the probability of recurrence of hernia. In addition, based on computed tomography (CT) or magnetic resonance imaging (MRI), the shapes and the sizes of defected areas of a abdominal wall can be obtained; through corresponding calculation, the shape and the size of the patch can be determined; and by utilizing a current-body dynamic injection technology, the patch is printed, the individual differences of patients need to be paid attention to, and improvement of a treatment effect of the repairing of the abdominal wall is facilitated.

Description

technical field [0001] The invention relates to the fields of biological 3D printing and restorative medicine, in particular, the invention relates to an elastic-enhanced mesh structure abdominal wall repair patch and a preparation method thereof. Background technique [0002] Hernia is a common abdominal wall defect disease. In the late 1980s, a new surgical method for the treatment of abdominal wall defects emerged. This surgery uses artificial biomaterials as abdominal repair patches to overcome traditional surgery. The destruction of normal tissue anatomy, and there is no tension around the tissue after surgical repair, so it is named "tension-free hernia repair". After more than 30 years of clinical use and continuous improvement, tension-free hernia repair has become the first choice for hernia surgery. [0003] An abdominal wall repair mesh is required in tension-free hernia repair surgery. At present, e-PTFE (expanded polytetrafluoroethylene) patch and PP (polyprop...

Claims

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Application Information

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IPC IPC(8): A61F2/00B29C64/386B33Y50/00A61L27/50
CPCA61F2/0063A61F2240/001A61L27/50B33Y50/00B29C64/386
Inventor 胡庆夕张仁南张海光王懿铭谢明亮
Owner SHANGHAI UNIV
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