Application of 1-deoxynojirimycin in treatment of diabetic cardiomyopathy and liver injury
A technology for deoxynojirimycin and diabetic cardiomyopathy, which is applied in the field of medicine, can solve the problems that there is no diabetic myocardial damage, special treatment drugs for reversing diabetic myocardial damage, etc. Effects of Cardiovascular Endothelial Cell Proliferation
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[0022] In order to facilitate a further understanding of the present invention, the examples provided below illustrate it in more detail. However, these examples are only for a better understanding of the invention and are not used to limit the scope or implementation principle of the invention, and the embodiments of the invention are not limited to the following content.
[0023] 1. Materials and methods
[0024] 1.1 Animals
[0025] Male C57BL / 6 mice, weighing 20-25 g, 8 weeks old, were provided by the Experimental Animal Center of Air Force Military Medical University.
[0026] 1.2 Reagent
[0027] Mulberry leaf extract (ML) was purchased from Xi'an Ruibo Biotechnology Co., Ltd., ingredient specification 1-DNJ5%, mulberry leaf flavonoids 10%; rutin (Rutin) was purchased from Solarbio company, purity ≥ 95%; quercetin (Quercetin ) was purchased from Solarbio, with a purity of ≥95%; 1-deoxynojirimycin (1-DNJ) was purchased from Yuanye Biology, with a purity of ≥98%; Acarbo...
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