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Anti-fatigue polygonatum sibiricum traditional Chinese medicine composition and health care wine thereof

A technology of health wine and composition, which is applied in the direction of drug combination, anti-toxic agent, medical formula, etc., can solve the problem of few varieties, achieve the effects of reducing fatigue, inhibiting the production of serum urea nitrogen and blood lactic acid, and improving exercise endurance

Pending Publication Date: 2019-09-27
HUAIHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The technology of health wine brewed by this method is simple, but due to the limitation of raw material types and other reasons, there are few varieties

Method used

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  • Anti-fatigue polygonatum sibiricum traditional Chinese medicine composition and health care wine thereof
  • Anti-fatigue polygonatum sibiricum traditional Chinese medicine composition and health care wine thereof
  • Anti-fatigue polygonatum sibiricum traditional Chinese medicine composition and health care wine thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Take white wine and add purified water to reduce the alcohol content respectively, and prepare liquor with alcoholic strength of 30% vol, 40% vol, 50% vol, 60% vol, 5 levels for later use.

[0031] Material processing: the jujube is pitted and dried to constant weight, and the sealwort is dried to constant weight. Polygonatum, medlar, jujube, American ginseng, astragalus, and poria were ground in a mortar, respectively, and passed through a 10-mesh sieve, a 20-mesh sieve, and a 50-mesh sieve for later use.

[0032] The prescription of the anti-fatigue sealwort health wine consists of 9-15 portions of sealwort, 9-15 portions of astragalus, 6-12 portions of medlar, 3-6 portions of American ginseng, 6-15 portions of jujube and 9-15 portions of poria cocos.

[0033] The formula of this embodiment is: sealwort 12g, astragalus 10g, medlar 6g, American ginseng 3g, jujube 7g, poria cocos 10g.

[0034] In a large number of previous experiments, the present invention found that ...

Embodiment 2

[0060] The formula of this embodiment is: sealwort 12g, astragalus 10g, medlar 6g, American ginseng 3g, jujube 7g, poria cocos 10g. The fixed material-liquid ratio is 1:5 (mass ratio), and the particle size of selected medicinal materials is 10 mesh, which is added to 250g of 50%vol base wine, and extracted at room temperature for 10d, 15d, 20d, 25d, 30d, 35d, each Three parallel samples were made for the extraction time of each category, and each parallel sample was repeated 3 times. The optimal extraction time is determined by detecting and analyzing the content of total saponins and crude polysaccharides in the extract.

[0061] The contents of total saponins and crude polysaccharides in the extracts of different extraction times were as follows: Figure 4 shown by Figure 4 It can be seen that with the extension of extraction time, the content of total saponins and crude polysaccharides also increased. The content of total saponins and crude polysaccharides increased gr...

Embodiment 3

[0063] Orthogonal experiments were designed based on the alcohol content of the base wine A, the particle size of medicinal materials B and the extraction time C to further optimize the extraction process and compare various extraction process conditions. The levels of each factor are shown in Table 1, and the results of the orthogonal test are shown in Table 2.

[0064] Table 1 Orthogonal experimental design

[0065]

[0066] Table 2 Orthogonal test result data

[0067]

[0068] Table 3 Summary analysis of the range of each factor

[0069]

[0070]

[0071] Table 3 is the results of the orthogonal test and the range analysis of each factor. Through intuitive analysis and range analysis, it can be seen that for the index component of total saponins alone, the optimal solution is A 3 B 1 C 1 D. 1 , for the crude polysaccharide index components alone, the optimal solution is A 3 B 3 C 3 D. 2 , the order of influence of each factor on total saponins is C>A>B...

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Abstract

The invention relates to an anti-fatigue polygonatum sibiricum traditional Chinese medicine composition. The traditional Chinese medicine composition comprises polygonatum sibiricum, astragalus membranaceus, lycium barbarum, panax quinquefolius, ziziphus jujube and poria cocos wolf. Components, such as polysaccharide and total saponin, in the raw materials of the traditional Chinese medicine composition are further efficiently and sufficiently extracted and prepared into polygonatum sibiricum health care wine, and the finally obtained polygonatum sibiricum health care wine is light yellowish-brown in color and mellow in bouquet, has unique herbal scent in volatile fume of wine, and is slight light, free from extraneous odor, and overall clear and transparent. Experiments show that the polygonatum sibiricum health care wine does not have obvious affects on weight and weight gain of mouse. Low-to-moderate dose of drinking of the polygonatum sibiricum health care wine can obviously improve the exercise tolerance of the mouse, reduce fatigue, reduce or inhibit generation of serum urea nitrogen and blood lactic acid of the mouse during long time motion, and is proved through experiments to have the efficacy of relieving physical fatigue.

Description

technical field [0001] The invention belongs to the technical application field of traditional Chinese medicine, and relates to an anti-fatigue Polygonatum traditional Chinese medicine composition and health wine. Background technique [0002] The development of society has led to the occurrence of sub-health states more and more frequently, and fatigue is the main manifestation of sub-health. According to surveys, fatigued people account for about 35% of the world's total population. Traditional Chinese medicine health food has a long history in my country and has a wide variety. Its research, development and diet methods are all based on TCM health theory and related health knowledge. China has a vast territory and relatively rich resources of traditional Chinese medicines. Based on the great breakthroughs in the research on the pharmacology and efficacy of Chinese medicinal materials in recent years, the development of health-care wine with Chinese medicinal materials a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P39/00C12G3/05C12G3/055
CPCA61K9/0095A61K36/076A61K36/258A61K36/481A61K36/725A61K36/815A61K36/8969A61K2236/333A61P39/00C12G3/05C12G3/055A61K2300/00
Inventor 梁娟伍贤进叶漪李胜华曹凤
Owner HUAIHUA UNIV
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