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Method for separating out and extracting high-purity malic acid

A malic acid, high-purity technology, applied in the separation/purification of carboxylic acid compounds, chemical instruments and methods, preparation of carboxylate, etc., to achieve the effects of high crystal purity, increased concentration, reduced concentration cost and difficulty in decolorization

Inactive Publication Date: 2019-09-24
ANHUI BBCA FERMENTATION TECH ENG RES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problems existing in the existing malic acid production process, and propose a method for producing high-purity malic acid by using calcium hydrogen malate crystallization method

Method used

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Embodiment 1

[0023] This embodiment provides a method for separating and extracting high-purity malic acid. The method uses the fermented liquid (rich in calcium malate) obtained by fermentation to produce malic acid as a raw material, and performs the following operations:

[0024] (1) 30.67kg fermented liquid is heated to 70 ℃, centrifuged, obtain filtrate 21.96kg and calcium malate wet solid 7.98kg;

[0025] (2) Mix the wet solid of calcium malate in step (1) with 5.63kg of water to adjust slurry, add sulfuric acid until the pH of the system is 3.0 for acidolysis, and then filter at 75°C to obtain 5.43kg of filter cake and 10.21kg of filtrate; The filtrate was cooled to 15°C and filtered to obtain 4.73 kg of wet crystals of calcium hydrogen malate;

[0026] (3) Mix the wet calcium hydrogen malate crystals obtained in step (2) with 3.35kg of water for pulping, add sulfuric acid and carry out acidolysis until the calcium hydrogen malate is all converted into malic acid, and collect 6.32 k...

Embodiment 2

[0029] This embodiment provides a method for separating and extracting high-purity malic acid. The method uses the fermented liquid (rich in calcium malate) obtained by enzymatic conversion to produce malic acid as a raw material, and performs the following operations:

[0030] (1) 21.67kg of fermented liquid was heated to 80°C, and centrifuged to obtain 5.78kg of calcium malate wet solid;

[0031] (2) Get step (1) calcium malate wet solid 1.5kg, mix slurry with 3kg water, then add embodiment 1 step (4) mother liquor obtained after malic acid is crystallized, until system pH is 2.9 and carry out acidolysis , and then filtered at 85°C to obtain 6.75kg of filtrate; the filtrate was concentrated to 2.435kg, cooled to 10°C, and filtered to obtain 1.983kg of wet crystals of calcium hydrogen malate;

[0032] (3) Mix the wet crystals of calcium hydrogen malate obtained in step (2) with 1.7kg water for slurry adjustment, add sulfuric acid and carry out acidolysis until calcium hydroge...

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Abstract

The invention relates to a method for separating out and extracting high-purity malic acid. The method includes the following steps of firstly, separating solid and liquid and collecting the solid by using calcium-malate-containing fermentation broth obtained by producing malic acid through a fermentation method or an enzymatic conversion method as the raw material; secondly, mixing the obtained solid with water, conducting acidolysis to convert the calcium malate into calcium hydrogen malate, conducting filtering, collecting filtrate, crystallizing the calcium hydrogen malate contained in the filtrate, and collecting crystals; thridly, mixing the obtained crystals with water, conducting acidolysis to convert the whole calcium hydrogen malate into malic acid, separating solid and liquid, collecting malic acid acidolysis liquid, and conducting further processing to obtain the malic acid with the purity of 99.0% or above. According to the method, by converting calcium-malate-containing pulp into calcium hydrogen malate and then conducting crystallizing, the concentration of the malic acid acidolysis liquid can be improved, the pigment of the acidolysis liquid is reduced, the concentrating cost and decoloring difficult of the subsequent process are reduced, and the finally-obtained malic acid product is high in purity and quality.

Description

technical field [0001] The invention relates to the field of food chemical industry, in particular to a method for separating and extracting high-purity malic acid. Background technique [0002] Malic acid, also known as 2-hydroxysuccinic acid, has two stereoisomers due to an asymmetric carbon atom in the molecule. In nature, it exists in three forms, namely D-malic acid, L-malic acid and its mixture DL-malic acid. Malic acid is a white crystal or crystalline powder, which has strong hygroscopicity and is easily soluble in water and ethanol. Has a particularly pleasant sour taste. Malic acid is mainly used in the food and pharmaceutical industries. [0003] At present, its production methods include chemical synthesis, fermentation and enzymatic production processes. The chemical synthesis method requires large investment and high technical requirements, and the synthesized product is DL-malic acid. The commonly used methods for extracting L-malic acid from malic acid f...

Claims

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Application Information

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IPC IPC(8): C07C51/41C07C51/02C07C51/43C07C59/245
CPCC07C51/412C07C51/02C07C51/43C07C59/245
Inventor 潘声龙胡富贵张渊纪传侠
Owner ANHUI BBCA FERMENTATION TECH ENG RES
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