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Medical cold application plaster and preparation method thereof

A technology of cold compress and formulation, which is applied in the field of medical supplies and can solve problems such as low water content and poor penetration of active ingredients

Pending Publication Date: 2019-08-20
广州市白云区大荣精细化工有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The cataplasms in the prior art have the disadvantages of low water content and poor penetration effect of active ingredients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0036] A preparation method of medical cold compress, comprising the following steps:

[0037] 1) Mix the sodium polyacrylate, disodium EDTA, and tartaric acid in the prescribed amount evenly to obtain the oil phase mixture, which is set aside;

[0038] 2) Add the glycerin of the formula amount into the mixing tank, then add the oil phase mixture into the mixing tank, stir evenly, and set aside;

[0039] 3) Add the water of the formula amount into the water phase bucket, then add the formula amount of aluminum glyoxate into the water phase bucket, stir evenly, and set aside;

[0040] 4) Add the preservatives and functional additives of the formulated amount to the ethanol of the formulated amount, after dissolving, add them into the mixing bucket of step 2), and stir evenly;

[0041] 5) Pour all the raw materials in the water phase barrel of step 3) into the mixing barrel of step 4), seal and stir, and after stirring for 3-5 minutes, turn on the vacuum pump, control the vacuu...

Embodiment 1

[0045] A medical cold compress, which is composed of a backing layer, a gel layer, and an anti-adhesive layer. The gel layer is prepared from the following components in terms of mass percentage: sodium polyacrylate 4%, glycylic aluminum 0.08 %, disodium EDTA 0.11%, tartaric acid 0.15%, glycerin 21%, caffeine 0.15%, potassium sorbate 0.1%, hydrolyzed collagen 0.1%, ginseng extract 0.1%, hyaluronic acid 0.01%, ethanol 1%, balance of water.

[0046] A preparation method of medical cold compress, comprising the following steps:

[0047] 1) Mix the sodium polyacrylate, disodium EDTA, and tartaric acid in the prescribed amount evenly to obtain the oil phase mixture, which is set aside;

[0048] 2) Add the glycerin of the formula amount into the mixing tank, then add the oil phase mixture into the mixing tank, stir evenly, and set aside;

[0049] 3) Add the water of the formula amount into the water phase bucket, then add the formula amount of aluminum glyoxate into the water phas...

Embodiment 2

[0055] A medical cold compress, which is composed of a backing layer, a gel layer, and an anti-adhesive layer. The gel layer is prepared from the following components in terms of mass percentage: sodium polyacrylate 5.2%, aluminum glycylate 0.12 %, disodium EDTA 0.12%, tartaric acid 0.22%, glycerin 25%, potassium sorbate 0.1%, hydrolyzed collagen 0.1%, snail extract 0.5%, ethanol 1%, and the balance water.

[0056] A preparation method of medical cold compress, comprising the following steps:

[0057] 1) Mix the sodium polyacrylate, disodium EDTA, and tartaric acid in the prescribed amount evenly to obtain the oil phase mixture, which is set aside;

[0058] 2) Add the glycerin of the formula amount into the mixing tank, then add the oil phase mixture into the mixing tank, stir evenly, and set aside;

[0059] 3) Add the water of the formula amount into the water phase bucket, then add the formula amount of aluminum glyoxate into the water phase bucket, stir evenly, and set asi...

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PUM

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Abstract

The invention discloses medical cold application plaster. The medical cold application plaster consists of a back lining layer, a gel layer and an antiseizing layer and is characterized in that the gel layer is prepared from the following components in percentage by mass of 4%-5.2% of sodium polyacrylate, 0.08%-0.12% of dihydroxyaluminum aminoacetate, 0.11%-0.12% of ethylenediaminetetraacetic aciddisodium salt, 0.15%-0.22% of tartaric acid, 21%-25% of glycerine, 0.01%-0.1% of a preservative, 0.1%-0.5% of a functional additive, 0.5%-2% of ethanol and the balance water. The invention further discloses a preparation method of the medical cold application plaster. The medical cold application plaster has high molecular gelatin being high in water content, effective components can rapidly penetrate into the fat layer, impregnate into subcutaneous tissue and achieve favorable effect through transdermic absorption.

Description

technical field [0001] The invention belongs to the technical field of medical supplies, and in particular relates to a medical cold compress and a preparation method thereof. Background technique [0002] Catapult is a kind of external preparation. Compared with other external preparations, such as ointment, coating, spray, etc., it has the characteristics of convenient use and simple preparation process. Compared with traditional plasters, since its matrix is ​​made of water-based polymer materials, it has better adhesion and is less prone to allergies when used for a long time, and has better safety. The cataplasms in the prior art have the disadvantages of low water content and poor penetration effect of active ingredients. Contents of the invention [0003] Aiming at the deficiencies in the prior art, the first object of the present invention is to provide a medical cold compress, which has a polymer gel with high water content, which can make the active ingredients ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K47/32A61K47/18A61K47/12A61K36/752A61K38/39A61P17/00A61K35/618A61K31/522A61K31/728
CPCA61K9/7023A61K47/32A61K47/183A61K47/12A61K36/23A61K36/185A61K36/752A61K36/53A61K35/618A61K36/258A61K38/39A61K31/522A61K31/728A61P17/00A61K2300/00
Inventor 胡志标
Owner 广州市白云区大荣精细化工有限公司
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