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Anti-gout drug

An anti-gout and effective technology, applied in the directions of drug combination, medical preparations containing active ingredients, pharmaceutical formulations, etc., can solve problems such as large side effects and poor efficacy, and achieve the effects of low toxicity, lowering uric acid levels, and obvious effects.

Inactive Publication Date: 2019-05-31
TONGHUA NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Poor curative effect and large side effects have become the bottleneck of its clinical application

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A kind of medicine with anti-gout effect, the raw materials in the formula are made according to the following parts by weight: 60 grams of Kudingcha (Ilex Ilex genus Kudingcha species), 90 grams of wolfberry, 30 grams of walnut kernels, and 40 grams of corn silk , raw job's tears 20 grams, prepared tablet.

[0017] Specific steps:

[0018] Take 60 grams of Kudingcha, decoct twice for 0.5 hours each time, collect the decoction, concentrate, evaporate to dryness to obtain a dry extract.

[0019] 90 grams of wolfberry, 30 grams of walnut kernels, 40 grams of corn silk, and 20 grams of raw job's tears, mixed and decocted twice, each time for 0.5 hours, collected the extract, concentrated and evaporated to dryness.

[0020] The extract is pulverized, mixed and added with dextrin and an appropriate amount of binder, granulated by wet method, dried and sized, added with an appropriate amount of talcum powder, and compressed into tablets to obtain tablets, each 0.3 g.

[002...

Embodiment 2

[0025] A kind of medicine with anti-gout effect, the raw materials in the formula are made according to the following parts by weight: 60 grams of Kudingcha (Ilex Ilex genus Kudingcha species), 90 grams of wolfberry, 30 grams of walnut kernels, and 40 grams of corn silk , 20 grams of raw barley, prepared into capsules.

[0026] Specific steps:

[0027] Take 60 grams of Kudingcha, decoct twice for 0.5 hours each time, collect the decoction, concentrate, evaporate to dryness to obtain a dry extract.

[0028] 90 grams of wolfberry, 30 grams of walnut kernels, 40 grams of corn silk, 20 grams of raw barley, mixed and extracted, mixed and decocted twice, each time for 0.5 hours, the extract was collected, concentrated and evaporated to dryness, and the extract was frozen dry.

[0029] The extract is pulverized and mixed, and then filled into capsules to obtain capsules, each 0.25 g.

[0030] Efficacy: anti-inflammatory, analgesic, accelerate uric acid metabolism, inhibit uric aci...

experiment example 1

[0034] Effect of a drug (Example 2) with anti-gout effect on mouse hyperuricemia model

[0035] After referring to the literature, related methods were adopted, and allopurinol was used as the control experiment. The results are shown in Table 1.

[0036]

[0037] Conclusion: Show by above-mentioned experimental result, a kind of medicine that has anti-gout effect of the present invention, to the influence of mouse hyperuricemia model, its effect has is better than allopurinol, shows that the present invention is a significant curative effect anti-gout. Medicines for gout.

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PUM

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Abstract

The invention relates to an anti-gout drug. The drug comprises, by weight, 3-9g of broadleaf holly leaf (of ilex of holly family), 6-12g of medlar, 5-10g of kernel, 30-60g of corn stigma and 18g of semen coicis. The method is simple, the selected raw materials are homologous to medicine with small toxic and side effects, and the drug has the effects of protecting the cardio-cerebral blood vessels,the liver and the kidney and anti-inflammatory and analgesic effects, and is the ideal anti-gout drug.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a medicine with anti-gout effect. Background technique [0002] In the prior art, gout (scientific name: metabolic arthritis) is a disease caused by accumulation of uric acid due to purine metabolism disorder, which belongs to a kind of arthritis, also known as metabolic arthritis. Clinical manifestations include hyperuricemia, gouty acute arthritis, tophi deposition, characteristic chronic arthritis and arthritic deformity, often involving the kidney, causing chronic interstitial nephritis and renal uric acid stones. Epidemiology shows that the prevalence of gout in Europe and America is 0.2%-1.7%. In my country, the incidence of gout has been on the rise in recent years, and the prevalence rate of the general population in my country is about 1.14%. The incidence of gout in rich areas of my country is significantly higher than that in rural areas. Gout has serious...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P19/06
Inventor 刘雪坤王艳秋马珑廷耿晓宇朱俊义李靖媛
Owner TONGHUA NORMAL UNIV
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