Traditional Chinese medicine composition for treating cancer related fatigue of patient suffering from malignant tumor

A technology for cancer-related fatigue and malignant tumors, which is applied in the field of traditional Chinese medicine compositions for the treatment of cancer-related fatigue in patients with malignant tumors, can solve the problems of low efficacy evidence level, no improvement in fatigue symptoms, limitations, etc., and achieves remarkable therapeutic effect, Good medicinal effect

Inactive Publication Date: 2019-05-31
陆明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(2) Stimulants: The most commonly used stimulants for cancer-related fatigue are methylphenidate and modafinil, but the level of evidence for the efficacy of these two drugs is low, and higher evidence is needed for further support. Methylphenidate Methylphenidate is an amphetamine-like central nervous system stimulant. It can take effect quickly after taking the drug, and the effect lasts for a long time. In a randomized double-blind placebo-controlled trial conducted by Bruera et al., it was found that methylphenidate can relieve Cancer-related fatigue, but placebo effects cannot be ruled out
The study by Morrow GR et al. found that although modafinil can improve the fatigue symptoms of patients after chemotherapy, this effect is limited to severe fatigue
At present, due to the limited number of studies on modafinil and the efficacy of modafinil in improving cancer-related fatigue is still to be determined, it is not recommended to use modafinil for the treatment of cancer-related fatigue
(3) Antidepressants: Fatigue and depression are closely related. Some randomized controlled trials use serotonin receptor blockers (paroxetine, etc.) Symptoms do not improve
(4) Hormones: Steroids can improve the quality of life of patients with terminal cancer and relieve fatigue symptoms. Yennurajalingam S et al. used dexamethasone to treat 84 patients with advanced cancer. The results showed that dexamethasone could relieve cancer-related fatigue. However, The side effects of this type of drugs are very large, and their routine use is limited. Therefore, the above data show that western medicine is relatively limited in alleviating cancer-related fatigue.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The traditional Chinese medicine composition for treating cancer-related fatigue in patients with malignant tumors of this embodiment consists of the following components in parts by weight: 15 parts of Astragalus, 15 parts of Codonopsis pilosula, 15 parts of fried Atractylodes macrocephala, 15 parts of roasted licorice, 10 parts of angelica, and 12 parts of tangerine peel 6 parts of cohosh, 6 parts of Bupleurum, 15 parts of Rhodiola and 15 parts of Agrimony.

[0029] The above-mentioned Chinese medicine composition was added into water, the mass ratio of the Chinese medicine composition to water was 1:10, after simmering for 40 minutes, the filtrate was filtered to obtain 500 mL of decoction, twice a day, and served warm.

[0030] Patient Li, 1 year after radiotherapy and chemotherapy after radical resection of breast cancer, took the decoction of the traditional Chinese medicine composition of this embodiment, 2 times a day, and took medicine for 4 weeks. Before taking...

Embodiment 2

[0033]The traditional Chinese medicine composition for treating cancer-related fatigue in patients with malignant tumors in this embodiment is composed of the following components in parts by weight: 10 parts of Astragalus, 10 parts of Codonopsis pilosula, 10 parts of fried Atractylodes macrocephala, 10 parts of roasted licorice, 6 parts of angelica, 20 parts of tangerine peel 10 parts of Cimicifuga, 10 parts of Bupleurum, 25 parts of Rhodiola and 25 parts of Agrimony.

[0034] The above-mentioned Chinese medicine composition was added into water, the mass ratio of the Chinese medicine composition to water was 1:10, after simmering for 40 minutes, the filtrate was filtered to obtain 500 mL of decoction, twice a day, and served warm.

[0035] Patient Xu, more than 2 years after radical resection of breast cancer, took the decoction of the traditional Chinese medicine composition of this embodiment, once a day, for 4 weeks. Before taking this decoction, one suffers from lassitud...

Embodiment 3

[0038] The traditional Chinese medicine composition for treating cancer-related fatigue in patients with malignant tumors in this embodiment consists of the following components in parts by weight: 25 parts of astragalus, 20 parts of codonopsis, 20 parts of fried Atractylodes macrocephala, 25 parts of roasted licorice, 15 parts of angelica, and 10 parts of tangerine peel , 2 parts Cimicifuga, 4 parts Bupleurum, 10 parts Rhodiola and 10 parts Agrimony.

[0039] The above-mentioned Chinese medicine composition was added into water, the mass ratio of the Chinese medicine composition to water was 1:10, after simmering for 40 minutes, the filtrate was filtered to obtain 500 mL of decoction, twice a day, and served warm.

[0040] Patient Shi, two months after colon cancer surgery, took the decoction of the Chinese medicine composition of this embodiment, once a day, for 3 weeks. Before taking this decoction, she had poor energy, soft knees and swollen legs, shortness of breath, fati...

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition for treating cancer related fatigue of a patient suffering from a malignant tumor. The traditional Chinese medicine composition is prepared from radix astragali, radix codcnopsitis pilosulas or ginseng, roasted rhizoma atractylodis macrocephalae, prepared liquorice roots, radix angelicae sinensis, dried tangerine or orange peel, rhizoma cimicifugae, radix bupleuri, rhodiola rosea roots and hairyvein agrimonia herb and buds. The rhodiola rosea roots have the functions of strengthening the body resistance, benefiting Qi, nourishing blood and resisting fatigue and oxidation; the hairyvein agrimonia herb and buds can treat blood trouble, cough and asthma caused by the tumor and has the effects on weakness and shortness of breathdue to chronic disease of the patient, and after the hairyvein agrimonia herb and buds are matched with the rhodiola rosea roots, the treatment effect of relieving fatigue can be achieved. By addingthe radix codcnopsitis pilosulas or the ginseng, the effects of invigorating Qi, strengthening the spleen and tonifying healthy Qi of the human body are achieved; the prepared liquorice roots can treat tireness and weakness; the roasted rhizoma atractylodis macrocephalae can tonify the spleen and clear damp away, make transportation and transformation balanced and make the Qi and blood activated,and when the radix astragali is matched with the roasted rhizoma atractylodis macrocephalae, the spleen Qi can be tonified; when the radix astragali is matched with the radix angelicae sinensis, the effects of tonifying Qi and nourishing blood can be achieved; the rhizoma cimicifugae and the radix bupleuri disperse stagnated liver Qi to relieve depression, the dried tangerine or orange peel regulates Qi-flowing for strengthening the spleen, all the medicine materials are combined to treat the liver and the spleen and tonify the Qi and the blood, the usage of the medicine materials is considerate, and the traditional Chinese medicine composition can treat the cancer related fatigue of the patient suffering from the malignant tumor.

Description

technical field [0001] The invention belongs to the technical field of breast cancer treatment, and in particular relates to a traditional Chinese medicine composition for treating cancer-related fatigue in patients with malignant tumors. Background technique [0002] With the improvement of diagnosis technology and treatment level, the survival period of cancer is increasing year by year. At present, about 2 / 3 of cancer patients can survive for five years or more. Therefore, cancer is now mostly regarded as a disease. Chronic diseases are just like diabetes, hypertension and coronary heart disease. Now, more and more clinical research focuses and patients' attention is shifted to how to minimize treatment-related side effects and improve the quality of life of cancer patients. Cancer patients believe that fatigue is the most disturbing symptom related to cancer and cancer treatment, and it even affects the quality of life more than pain, nausea and vomiting. Because most c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P35/00A61P39/00
Inventor 陆明
Owner 陆明
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